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A novel susceptibility locus in the IL12B region is associated with the pathophysiology of Takayasu arteritis through IL-12p40 and IL-12p70 production.
Nakajima T, Yoshifuji H, Shimizu M, Kitagori K, Murakami K, Nakashima R, Imura Y, Tanaka M, Ohmura K, Matsuda F, Terao C, Mimori T. Nakajima T, et al. Among authors: shimizu m. Arthritis Res Ther. 2017 Sep 6;19(1):197. doi: 10.1186/s13075-017-1408-8. Arthritis Res Ther. 2017. PMID: 28874185 Free PMC article.
Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis.
Ito Y, Usui T, Kobayashi S, Iguchi-Hashimoto M, Ito H, Yoshitomi H, Nakamura T, Shimizu M, Kawabata D, Yukawa N, Hashimoto M, Sakaguchi N, Sakaguchi S, Yoshifuji H, Nojima T, Ohmura K, Fujii T, Mimori T. Ito Y, et al. Among authors: shimizu m. Arthritis Rheum. 2009 Aug;60(8):2294-303. doi: 10.1002/art.24687. Arthritis Rheum. 2009. PMID: 19644886 Free article.
Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis--a genome-wide study combined with immunological analyses.
Terao C, Ohmura K, Katayama M, Takahashi M, Kokubo M, Diop G, Toda Y, Yamamoto N; Human Disease Genomics Working Group; Rheumatoid Arthritis (RA) Clinical and Genetic Study Consortium; Shinkura R, Shimizu M, Gut I, Heath S, Melchers I, Manabe T, Lathrop M, Mimori T, Yamada R, Matsuda F. Terao C, et al. Among authors: shimizu m. PLoS One. 2011;6(6):e20457. doi: 10.1371/journal.pone.0020457. Epub 2011 Jun 3. PLoS One. 2011. PMID: 21673997 Free PMC article.
Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-κB and increased STAT5 signals.
Iguchi-Hashimoto M, Usui T, Yoshifuji H, Shimizu M, Kobayashi S, Ito Y, Murakami K, Shiomi A, Yukawa N, Kawabata D, Nojima T, Ohmura K, Fujii T, Mimori T. Iguchi-Hashimoto M, et al. Among authors: shimizu m. PLoS One. 2011;6(10):e27020. doi: 10.1371/journal.pone.0027020. Epub 2011 Oct 27. PLoS One. 2011. PMID: 22046434 Free PMC article.
Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population.
Terao C, Yoshifuji H, Kimura A, Matsumura T, Ohmura K, Takahashi M, Shimizu M, Kawaguchi T, Chen Z, Naruse TK, Sato-Otsubo A, Ebana Y, Maejima Y, Kinoshita H, Murakami K, Kawabata D, Wada Y, Narita I, Tazaki J, Kawaguchi Y, Yamanaka H, Yurugi K, Miura Y, Maekawa T, Ogawa S, Komuro I, Nagai R, Yamada R, Tabara Y, Isobe M, Mimori T, Matsuda F. Terao C, et al. Among authors: shimizu m. Am J Hum Genet. 2013 Aug 8;93(2):289-97. doi: 10.1016/j.ajhg.2013.05.024. Epub 2013 Jul 3. Am J Hum Genet. 2013. PMID: 23830516 Free PMC article.
Association between antinuclear antibodies and the HLA class II locus and heterogeneous characteristics of staining patterns: the Nagahama study.
Terao C, Ohmura K, Yamada R, Kawaguchi T, Shimizu M, Tabara Y, Takahashi M, Setoh K, Nakayama T, Kosugi S, Sekine A, Matsuda F, Mimori T; Nagahama Study Group. Terao C, et al. Among authors: shimizu m. Arthritis Rheumatol. 2014 Dec;66(12):3395-403. doi: 10.1002/art.38867. Arthritis Rheumatol. 2014. PMID: 25186300
6,038 results