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RIG-I recognizes metabolite-capped RNAs as signaling ligands.
Schweibenz BD, Solotchi M, Hanpude P, Devarkar SC, Patel SS. Schweibenz BD, et al. Among authors: solotchi m. Nucleic Acids Res. 2023 Aug 25;51(15):8102-8114. doi: 10.1093/nar/gkad518. Nucleic Acids Res. 2023. PMID: 37326006 Free PMC article.
The NS1 protein of influenza B virus binds 5'-triphosphorylated dsRNA to suppress RIG-I activation and the host antiviral response.
Woltz R, Schweibenz B, Tsutakawa SE, Zhao C, Ma L, Shurina B, Hura GL, John R, Vorobiev S, Swapna G, Solotchi M, Tainer JA, Krug RM, Patel SS, Montelione GT. Woltz R, et al. Among authors: solotchi m. bioRxiv [Preprint]. 2024 Jan 24:2023.09.25.559316. doi: 10.1101/2023.09.25.559316. bioRxiv. 2024. PMID: 38328244 Free PMC article. Preprint.