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Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest.
Mills RJ, Titmarsh DM, Koenig X, Parker BL, Ryall JG, Quaife-Ryan GA, Voges HK, Hodson MP, Ferguson C, Drowley L, Plowright AT, Needham EJ, Wang QD, Gregorevic P, Xin M, Thomas WG, Parton RG, Nielsen LK, Launikonis BS, James DE, Elliott DA, Porrello ER, Hudson JE. Mills RJ, et al. Among authors: launikonis bs. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8372-E8381. doi: 10.1073/pnas.1707316114. Epub 2017 Sep 15. Proc Natl Acad Sci U S A. 2017. PMID: 28916735 Free PMC article.
Dantrolene requires Mg2+ to arrest malignant hyperthermia.
Choi RH, Koenig X, Launikonis BS. Choi RH, et al. Among authors: launikonis bs. Proc Natl Acad Sci U S A. 2017 May 2;114(18):4811-4815. doi: 10.1073/pnas.1619835114. Epub 2017 Apr 3. Proc Natl Acad Sci U S A. 2017. PMID: 28373535 Free PMC article.
Ryanodine receptor leak triggers fiber Ca2+ redistribution to preserve force and elevate basal metabolism in skeletal muscle.
Lamboley CR, Pearce L, Seng C, Meizoso-Huesca A, Singh DP, Frankish BP, Kaura V, Lo HP, Ferguson C, Allen PD, Hopkins PM, Parton RG, Murphy RM, van der Poel C, Barclay CJ, Launikonis BS. Lamboley CR, et al. Among authors: launikonis bs. Sci Adv. 2021 Oct 29;7(44):eabi7166. doi: 10.1126/sciadv.abi7166. Epub 2021 Oct 27. Sci Adv. 2021. PMID: 34705503 Free PMC article.
66 results