Liu Y - Search Results

1

Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth.

Lyu J, Yang EJ, Head SA, Ai N, Zhang B, Wu C, Li RJ, Liu Y, Yang C, Dang Y, Kwon HJ, Ge W, Liu JO, Shim JS. Lyu J, et al. Among authors: liu y, liu jo. Cancer Lett. 2017 Nov 28;409:91-103. doi: 10.1016/j.canlet.2017.09.009. Epub 2017 Sep 18. Cancer Lett. 2017. PMID: 28923401 Free PMC article.

2

PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A.

Liu Y, Yang EJ, Zhang B, Miao Z, Wu C, Lyu J, Tan K, Poon TCW, Shim JS. Liu Y, et al. Cancer Lett. 2018 Nov 1;436:28-37. doi: 10.1016/j.canlet.2018.08.011. Epub 2018 Aug 14. Cancer Lett. 2018. PMID: 30118842

3

Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking.

Lyu J, Yang EJ, Head SA, Ai N, Zhang B, Wu C, Li RJ, Liu Y, Chakravarty H, Zhang S, Tam KY, Dang Y, Kwon HJ, Ge W, Liu JO, Shim JS. Lyu J, et al. Among authors: liu y, liu jo. Int J Biol Sci. 2018 Jun 23;14(10):1175-1185. doi: 10.7150/ijbs.26011. eCollection 2018. Int J Biol Sci. 2018. PMID: 30123067 Free PMC article.

4

BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition.

Zhang B, Lyu J, Liu Y, Wu C, Yang EJ, Pardeshi L, Tan K, Wong KH, Chen Q, Xu X, Deng CX, Shim JS. Zhang B, et al. Among authors: liu y. Oncogene. 2018 Dec;37(49):6341-6356. doi: 10.1038/s41388-018-0408-8. Epub 2018 Jul 24. Oncogene. 2018. PMID: 30042414

5

Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells.

Wu C, Lyu J, Yang EJ, Liu Y, Zhang B, Shim JS. Wu C, et al. Among authors: liu y. Nat Commun. 2018 Aug 10;9(1):3212. doi: 10.1038/s41467-018-05694-4. Nat Commun. 2018. PMID: 30097580 Free PMC article.

6

Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells.

Zhang B, Lyu J, Yang EJ, Liu Y, Wu C, Pardeshi L, Tan K, Chen Q, Xu X, Deng CX, Shim JS. Zhang B, et al. Among authors: liu y. Acta Pharm Sin B. 2020 Apr;10(4):615-627. doi: 10.1016/j.apsb.2019.08.008. Epub 2019 Sep 5. Acta Pharm Sin B. 2020. PMID: 32322466 Free PMC article.

7

Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKT.

Liu Y, Yang EJ, Shi C, Mou PK, Zhang B, Wu C, Lyu J, Shim JS. Liu Y, et al. Int J Biol Sci. 2020 Mar 25;16(11):1774-1784. doi: 10.7150/ijbs.42197. eCollection 2020. Int J Biol Sci. 2020. PMID: 32398948 Free PMC article.

8

Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics.

Lyu J, Yang EJ, Zhang B, Wu C, Pardeshi L, Shi C, Mou PK, Liu Y, Tan K, Shim JS. Lyu J, et al. Among authors: liu y. Nat Commun. 2020 Oct 9;11(1):5105. doi: 10.1038/s41467-020-18872-0. Nat Commun. 2020. PMID: 33037191 Free PMC article.

9

Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression.

Shi C, Yang EJ, Liu Y, Mou PK, Ren G, Shim JS. Shi C, et al. Among authors: liu y. Oncogene. 2021 Feb;40(5):937-950. doi: 10.1038/s41388-020-01580-w. Epub 2020 Dec 8. Oncogene. 2021. PMID: 33293694

10

Revisiting Non-Cancer Drugs for Cancer Therapy.

Yang EJ, Wu C, Liu Y, Lv J, Sup Shim J. Yang EJ, et al. Among authors: liu y. Curr Top Med Chem. 2016;16(19):2144-55. doi: 10.2174/1568026616666160216154441. Curr Top Med Chem. 2016. PMID: 26881712 Review.

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