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An amino-terminal signal peptide of Vfr protein negatively influences RopB-dependent SpeB expression and attenuates virulence in Streptococcus pyogenes.
Shelburne SA 3rd, Olsen RJ, Makthal N, Brown NG, Sahasrabhojane P, Watkins EM, Palzkill T, Musser JM, Kumaraswami M. Shelburne SA 3rd, et al. Among authors: makthal n. Mol Microbiol. 2011 Dec;82(6):1481-95. doi: 10.1111/j.1365-2958.2011.07902.x. Epub 2011 Nov 21. Mol Microbiol. 2011. PMID: 22040048 Free PMC article.
A naturally occurring single amino acid replacement in multiple gene regulator of group A Streptococcus significantly increases virulence.
Sanson M, O'Neill BE, Kachroo P, Anderson JR, Flores AR, Valson C, Cantu CC, Makthal N, Karmonik C, Fittipaldi N, Kumaraswami M, Musser JM, Olsen RJ. Sanson M, et al. Among authors: makthal n. Am J Pathol. 2015 Feb;185(2):462-71. doi: 10.1016/j.ajpath.2014.10.018. Epub 2014 Dec 2. Am J Pathol. 2015. PMID: 25476528 Free PMC article.
22 results