O'Shea JJ - Search Results

1

Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA.

Mowel WK, McCright SJ, Kotzin JJ, Collet MA, Uyar A, Chen X, DeLaney A, Spencer SP, Virtue AT, Yang E, Villarino A, Kurachi M, Dunagin MC, Pritchard GH, Stein J, Hughes C, Fonseca-Pereira D, Veiga-Fernandes H, Raj A, Kambayashi T, Brodsky IE, O'Shea JJ, Wherry EJ, Goff LA, Rinn JL, Williams A, Flavell RA, Henao-Mejia J. Mowel WK, et al. Immunity. 2017 Sep 19;47(3):435-449.e8. doi: 10.1016/j.immuni.2017.08.012. Immunity. 2017. PMID: 28930659 Free PMC article.

2

Viral FLIP impairs survival of activated T cells and generation of CD8+ T cell memory.

Wu Z, Roberts M, Porter M, Walker F, Wherry EJ, Kelly J, Gadina M, Silva EM, DosReis GA, Lopes MF, O'Shea J, Leonard WJ, Ahmed R, Siegel RM. Wu Z, et al. J Immunol. 2004 May 15;172(10):6313-23. doi: 10.4049/jimmunol.172.10.6313. J Immunol. 2004. PMID: 15128821

3

Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system.

Stumhofer JS, Laurence A, Wilson EH, Huang E, Tato CM, Johnson LM, Villarino AV, Huang Q, Yoshimura A, Sehy D, Saris CJ, O'Shea JJ, Hennighausen L, Ernst M, Hunter CA. Stumhofer JS, et al. Nat Immunol. 2006 Sep;7(9):937-45. doi: 10.1038/ni1376. Epub 2006 Aug 13. Nat Immunol. 2006. PMID: 16906166

4

Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals.

Villarino AV, Tato CM, Stumhofer JS, Yao Z, Cui YK, Hennighausen L, O'Shea JJ, Hunter CA. Villarino AV, et al. J Exp Med. 2007 Jan 22;204(1):65-71. doi: 10.1084/jem.20061198. Epub 2007 Jan 16. J Exp Med. 2007. PMID: 17227909 Free PMC article.

5

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation.

Laurence A, Tato CM, Davidson TS, Kanno Y, Chen Z, Yao Z, Blank RB, Meylan F, Siegel R, Hennighausen L, Shevach EM, O'shea JJ. Laurence A, et al. Immunity. 2007 Mar;26(3):371-81. doi: 10.1016/j.immuni.2007.02.009. Immunity. 2007. PMID: 17363300 Free article.

6

Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity.

Brydges SD, Mueller JL, McGeough MD, Pena CA, Misaghi A, Gandhi C, Putnam CD, Boyle DL, Firestein GS, Horner AA, Soroosh P, Watford WT, O'Shea JJ, Kastner DL, Hoffman HM. Brydges SD, et al. Immunity. 2009 Jun 19;30(6):875-87. doi: 10.1016/j.immuni.2009.05.005. Epub 2009 Jun 4. Immunity. 2009. PMID: 19501000 Free PMC article.

7

Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.

Durant L, Watford WT, Ramos HL, Laurence A, Vahedi G, Wei L, Takahashi H, Sun HW, Kanno Y, Powrie F, O'Shea JJ. Durant L, et al. Immunity. 2010 May 28;32(5):605-15. doi: 10.1016/j.immuni.2010.05.003. Epub 2010 May 20. Immunity. 2010. PMID: 20493732 Free PMC article.

8

Regulation of microRNA expression and abundance during lymphopoiesis.

Kuchen S, Resch W, Yamane A, Kuo N, Li Z, Chakraborty T, Wei L, Laurence A, Yasuda T, Peng S, Hu-Li J, Lu K, Dubois W, Kitamura Y, Charles N, Sun HW, Muljo S, Schwartzberg PL, Paul WE, O'Shea J, Rajewsky K, Casellas R. Kuchen S, et al. Immunity. 2010 Jun 25;32(6):828-39. doi: 10.1016/j.immuni.2010.05.009. Epub 2010 Jun 3. Immunity. 2010. PMID: 20605486 Free PMC article.

9

Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation.

Wei L, Vahedi G, Sun HW, Watford WT, Takatori H, Ramos HL, Takahashi H, Liang J, Gutierrez-Cruz G, Zang C, Peng W, O'Shea JJ, Kanno Y. Wei L, et al. Immunity. 2010 Jun 25;32(6):840-51. doi: 10.1016/j.immuni.2010.06.003. Immunity. 2010. PMID: 20620946 Free PMC article.

10

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5.

Yang XP, Ghoreschi K, Steward-Tharp SM, Rodriguez-Canales J, Zhu J, Grainger JR, Hirahara K, Sun HW, Wei L, Vahedi G, Kanno Y, O'Shea JJ, Laurence A. Yang XP, et al. Nat Immunol. 2011 Mar;12(3):247-54. doi: 10.1038/ni.1995. Epub 2011 Jan 30. Nat Immunol. 2011. PMID: 21278738 Free PMC article.

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