Jamwal R - Search Results

1

Multiplex and Label-Free Relative Quantification Approach for Studying Protein Abundance of Drug Metabolizing Enzymes in Human Liver Microsomes Using SWATH-MS.

Jamwal R, Barlock BJ, Adusumalli S, Ogasawara K, Simons BL, Akhlaghi F. Jamwal R, et al. J Proteome Res. 2017 Nov 3;16(11):4134-4143. doi: 10.1021/acs.jproteome.7b00505. Epub 2017 Oct 10. J Proteome Res. 2017. PMID: 28944677

2

Nonalcoholic Fatty Liver Disease and Diabetes Are Associated with Decreased CYP3A4 Protein Expression and Activity in Human Liver.

Jamwal R, de la Monte SM, Ogasawara K, Adusumalli S, Barlock BB, Akhlaghi F. Jamwal R, et al. Mol Pharm. 2018 Jul 2;15(7):2621-2632. doi: 10.1021/acs.molpharmaceut.8b00159. Epub 2018 Jun 11. Mol Pharm. 2018. PMID: 29792708 Free PMC article.

3

Ultra-high performance liquid chromatography tandem mass-spectrometry for simple and simultaneous quantification of cannabinoids.

Jamwal R, Topletz AR, Ramratnam B, Akhlaghi F. Jamwal R, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Mar 24;1048:10-18. doi: 10.1016/j.jchromb.2017.02.007. Epub 2017 Feb 6. J Chromatogr B Analyt Technol Biomed Life Sci. 2017. PMID: 28192758 Free PMC article.

4

Nonalcoholic Fatty Liver Disease (NAFLD) and Hepatic Cytochrome P450 (CYP) Enzymes.

Jamwal R, Barlock BJ. Jamwal R, et al. Pharmaceuticals (Basel). 2020 Aug 29;13(9):222. doi: 10.3390/ph13090222. Pharmaceuticals (Basel). 2020. PMID: 32872474 Free PMC article. Review.

5

Development and validation of an assay for a novel ghrelin receptor inverse agonist PF-5190457 and its major hydroxy metabolite (PF-6870961) by LC-MS/MS in human plasma.

Adusumalli S, Jamwal R, Leggio L, Akhlaghi F. Adusumalli S, et al. Among authors: jamwal r. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Nov 1;1130-1131:121820. doi: 10.1016/j.jchromb.2019.121820. Epub 2019 Oct 8. J Chromatogr B Analyt Technol Biomed Life Sci. 2019. PMID: 31670107

6

Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach.

Adusumalli S, Jamwal R, Obach RS, Ryder TF, Leggio L, Akhlaghi F. Adusumalli S, et al. Among authors: jamwal r. Drug Metab Dispos. 2019 Aug;47(8):874-882. doi: 10.1124/dmd.119.087015. Epub 2019 Jun 10. Drug Metab Dispos. 2019. PMID: 31182423 Free PMC article. Clinical Trial.

7

Perfluorooctanesulfonic acid (PFOS) administration shifts the hepatic proteome and augments dietary outcomes related to hepatic steatosis in mice.

Marques E, Pfohl M, Auclair A, Jamwal R, Barlock BJ, Sammoura FM, Goedken M, Akhlaghi F, Slitt AL. Marques E, et al. Among authors: jamwal r. Toxicol Appl Pharmacol. 2020 Dec 1;408:115250. doi: 10.1016/j.taap.2020.115250. Epub 2020 Sep 23. Toxicol Appl Pharmacol. 2020. PMID: 32979393 Free PMC article.

8

An 'Omics Approach to Unraveling the Paradoxical Effect of Diet on Perfluorooctanesulfonic Acid (PFOS) and Perfluorononanoic Acid (PFNA)-Induced Hepatic Steatosis.

Pfohl M, Marques E, Auclair A, Barlock B, Jamwal R, Goedken M, Akhlaghi F, Slitt AL. Pfohl M, et al. Among authors: jamwal r. Toxicol Sci. 2021 Apr 12;180(2):277-294. doi: 10.1093/toxsci/kfaa172. Toxicol Sci. 2021. PMID: 33483757 Free PMC article.

9

Perfluorooctanesulfonic Acid and Perfluorohexanesulfonic Acid Alter the Blood Lipidome and the Hepatic Proteome in a Murine Model of Diet-Induced Obesity.

Pfohl M, Ingram L, Marques E, Auclair A, Barlock B, Jamwal R, Anderson D, Cummings BS, Slitt AL. Pfohl M, et al. Among authors: jamwal r. Toxicol Sci. 2020 Dec 1;178(2):311-324. doi: 10.1093/toxsci/kfaa148. Toxicol Sci. 2020. PMID: 32991729 Free PMC article.

10

Bioanalytical strategies in drug discovery and development.

Thakur A, Tan Z, Kameyama T, El-Khateeb E, Nagpal S, Malone S, Jamwal R, Nwabufo CK. Thakur A, et al. Among authors: jamwal r. Drug Metab Rev. 2021 Aug;53(3):434-458. doi: 10.1080/03602532.2021.1959606. Epub 2021 Aug 23. Drug Metab Rev. 2021. PMID: 34310243 Review.

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