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Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner.
Deczkowska A, Matcovitch-Natan O, Tsitsou-Kampeli A, Ben-Hamo S, Dvir-Szternfeld R, Spinrad A, Singer O, David E, Winter DR, Smith LK, Kertser A, Baruch K, Rosenzweig N, Terem A, Prinz M, Villeda S, Citri A, Amit I, Schwartz M. Deczkowska A, et al. Among authors: prinz m. Nat Commun. 2017 Sep 28;8(1):717. doi: 10.1038/s41467-017-00769-0. Nat Commun. 2017. PMID: 28959042 Free PMC article.
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways.
Kierdorf K, Erny D, Goldmann T, Sander V, Schulz C, Perdiguero EG, Wieghofer P, Heinrich A, Riemke P, Hölscher C, Müller DN, Luckow B, Brocker T, Debowski K, Fritz G, Opdenakker G, Diefenbach A, Biber K, Heikenwalder M, Geissmann F, Rosenbauer F, Prinz M. Kierdorf K, et al. Among authors: prinz m. Nat Neurosci. 2013 Mar;16(3):273-80. doi: 10.1038/nn.3318. Epub 2013 Jan 20. Nat Neurosci. 2013. PMID: 23334579
Microglia fuel the learning brain.
Blank T, Goldmann T, Prinz M. Blank T, et al. Among authors: prinz m. Trends Immunol. 2014 Apr;35(4):139-40. doi: 10.1016/j.it.2014.02.005. Epub 2014 Mar 11. Trends Immunol. 2014. PMID: 24636251 Review.
Host microbiota constantly control maturation and function of microglia in the CNS.
Erny D, Hrabě de Angelis AL, Jaitin D, Wieghofer P, Staszewski O, David E, Keren-Shaul H, Mahlakoiv T, Jakobshagen K, Buch T, Schwierzeck V, Utermöhlen O, Chun E, Garrett WS, McCoy KD, Diefenbach A, Staeheli P, Stecher B, Amit I, Prinz M. Erny D, et al. Among authors: prinz m. Nat Neurosci. 2015 Jul;18(7):965-77. doi: 10.1038/nn.4030. Epub 2015 Jun 1. Nat Neurosci. 2015. PMID: 26030851 Free PMC article.
Origin, fate and dynamics of macrophages at central nervous system interfaces.
Goldmann T, Wieghofer P, Jordão MJ, Prutek F, Hagemeyer N, Frenzel K, Amann L, Staszewski O, Kierdorf K, Krueger M, Locatelli G, Hochgerner H, Zeiser R, Epelman S, Geissmann F, Priller J, Rossi FM, Bechmann I, Kerschensteiner M, Linnarsson S, Jung S, Prinz M. Goldmann T, et al. Among authors: prinz m. Nat Immunol. 2016 Jul;17(7):797-805. doi: 10.1038/ni.3423. Epub 2016 May 2. Nat Immunol. 2016. PMID: 27135602 Free PMC article.
Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation.
Wolf Y, Shemer A, Polonsky M, Gross M, Mildner A, Yona S, David E, Kim KW, Goldmann T, Amit I, Heikenwalder M, Nedospasov S, Prinz M, Friedman N, Jung S. Wolf Y, et al. Among authors: prinz m. J Exp Med. 2017 Apr 3;214(4):905-917. doi: 10.1084/jem.20160499. Epub 2017 Mar 22. J Exp Med. 2017. PMID: 28330904 Free PMC article.
A new fate mapping system reveals context-dependent random or clonal expansion of microglia.
Tay TL, Mai D, Dautzenberg J, Fernández-Klett F, Lin G, Sagar, Datta M, Drougard A, Stempfl T, Ardura-Fabregat A, Staszewski O, Margineanu A, Sporbert A, Steinmetz LM, Pospisilik JA, Jung S, Priller J, Grün D, Ronneberger O, Prinz M. Tay TL, et al. Among authors: prinz m. Nat Neurosci. 2017 Jun;20(6):793-803. doi: 10.1038/nn.4547. Epub 2017 Apr 17. Nat Neurosci. 2017. PMID: 28414331
703 results