Werz O - Search Results

1

Structure-Function Relationship Studies In Vitro Reveal Distinct and Specific Effects of Long-Chain Metabolites of Vitamin E.

Schmölz L, Wallert M, Rozzino N, Cignarella A, Galli F, Glei M, Werz O, Koeberle A, Birringer M, Lorkowski S. Schmölz L, et al. Among authors: werz o. Mol Nutr Food Res. 2017 Dec;61(12). doi: 10.1002/mnfr.201700562. Epub 2017 Nov 3. Mol Nutr Food Res. 2017. PMID: 28960703

2

The role of diacylglyceride generation by phospholipase D and phosphatidic acid phosphatase in the activation of 5-lipoxygenase in polymorphonuclear leukocytes.

Albert D, Pergola C, Koeberle A, Dodt G, Steinhilber D, Werz O. Albert D, et al. Among authors: werz o. J Leukoc Biol. 2008 Apr;83(4):1019-27. doi: 10.1189/jlb.0807531. Epub 2008 Jan 24. J Leukoc Biol. 2008. PMID: 18218859

3

Licofelone suppresses prostaglandin E2 formation by interference with the inducible microsomal prostaglandin E2 synthase-1.

Koeberle A, Siemoneit U, Bühring U, Northoff H, Laufer S, Albrecht W, Werz O. Koeberle A, et al. Among authors: werz o. J Pharmacol Exp Ther. 2008 Sep;326(3):975-82. doi: 10.1124/jpet.108.139444. Epub 2008 Jun 11. J Pharmacol Exp Ther. 2008. PMID: 18550688

4

Novel and potent inhibitors of 5-lipoxygenase product synthesis based on the structure of pirinixic acid.

Werz O, Greiner C, Koeberle A, Hoernig C, George S, Popescu L, Syha I, Schubert-Zsilavecz M, Steinhilber D. Werz O, et al. J Med Chem. 2008 Sep 11;51(17):5449-53. doi: 10.1021/jm800588x. Epub 2008 Aug 19. J Med Chem. 2008. PMID: 18710209

5

Pirinixic acid derivatives as novel dual inhibitors of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase.

Koeberle A, Zettl H, Greiner C, Wurglics M, Schubert-Zsilavecz M, Werz O. Koeberle A, et al. Among authors: werz o. J Med Chem. 2008 Dec 25;51(24):8068-76. doi: 10.1021/jm801085s. J Med Chem. 2008. PMID: 19053751

6

MK-886, an inhibitor of the 5-lipoxygenase-activating protein, inhibits cyclooxygenase-1 activity and suppresses platelet aggregation.

Koeberle A, Siemoneit U, Northoff H, Hofmann B, Schneider G, Werz O. Koeberle A, et al. Among authors: werz o. Eur J Pharmacol. 2009 Apr 17;608(1-3):84-90. doi: 10.1016/j.ejphar.2009.02.023. Epub 2009 Feb 23. Eur J Pharmacol. 2009. PMID: 19239910

7

Myrtucommulone, a natural acylphloroglucinol, inhibits microsomal prostaglandin E(2) synthase-1.

Koeberle A, Pollastro F, Northoff H, Werz O. Koeberle A, et al. Among authors: werz o. Br J Pharmacol. 2009 Mar;156(6):952-61. doi: 10.1111/j.1476-5381.2009.00070.x. Br J Pharmacol. 2009. PMID: 19298395 Free PMC article.

8

Identification of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 as functional targets of the anti-inflammatory and anti-carcinogenic garcinol.

Koeberle A, Northoff H, Werz O. Koeberle A, et al. Among authors: werz o. Biochem Pharmacol. 2009 May 1;77(9):1513-21. doi: 10.1016/j.bcp.2009.02.005. Epub 2009 Feb 21. Biochem Pharmacol. 2009. PMID: 19426689

9

Green tea epigallocatechin-3-gallate inhibits microsomal prostaglandin E(2) synthase-1.

Koeberle A, Bauer J, Verhoff M, Hoffmann M, Northoff H, Werz O. Koeberle A, et al. Among authors: werz o. Biochem Biophys Res Commun. 2009 Oct 16;388(2):350-4. doi: 10.1016/j.bbrc.2009.08.005. Epub 2009 Aug 6. Biochem Biophys Res Commun. 2009. PMID: 19665000

10

Curcumin blocks prostaglandin E2 biosynthesis through direct inhibition of the microsomal prostaglandin E2 synthase-1.

Koeberle A, Northoff H, Werz O. Koeberle A, et al. Among authors: werz o. Mol Cancer Ther. 2009 Aug;8(8):2348-55. doi: 10.1158/1535-7163.MCT-09-0290. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671757

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