Duncan JA - Search Results

1

NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR.

Feng H, Lenarcic EM, Yamane D, Wauthier E, Mo J, Guo H, McGivern DR, González-López O, Misumi I, Reid LM, Whitmire JK, Ting JP, Duncan JA, Moorman NJ, Lemon SM. Feng H, et al. Among authors: duncan ja. Nat Immunol. 2017 Dec;18(12):1299-1309. doi: 10.1038/ni.3853. Epub 2017 Oct 2. Nat Immunol. 2017. PMID: 28967880 Free PMC article.

2

The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals.

Williams KL, Lich JD, Duncan JA, Reed W, Rallabhandi P, Moore C, Kurtz S, Coffield VM, Accavitti-Loper MA, Su L, Vogel SN, Braunstein M, Ting JP. Williams KL, et al. Among authors: duncan ja. J Biol Chem. 2005 Dec 2;280(48):39914-24. doi: 10.1074/jbc.M502820200. Epub 2005 Oct 3. J Biol Chem. 2005. PMID: 16203735 Free PMC article.

3

Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC.

Willingham SB, Bergstralh DT, O'Connor W, Morrison AC, Taxman DJ, Duncan JA, Barnoy S, Venkatesan MM, Flavell RA, Deshmukh M, Hoffman HM, Ting JP. Willingham SB, et al. Among authors: duncan ja. Cell Host Microbe. 2007 Sep 13;2(3):147-59. doi: 10.1016/j.chom.2007.07.009. Cell Host Microbe. 2007. PMID: 18005730 Free PMC article.

4

ATP binding by monarch-1/NLRP12 is critical for its inhibitory function.

Ye Z, Lich JD, Moore CB, Duncan JA, Williams KL, Ting JP. Ye Z, et al. Among authors: duncan ja. Mol Cell Biol. 2008 Mar;28(5):1841-50. doi: 10.1128/MCB.01468-07. Epub 2007 Dec 26. Mol Cell Biol. 2008. PMID: 18160710 Free PMC article.

5

NLRX1 is a regulator of mitochondrial antiviral immunity.

Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, Accavitti-Loper MA, Madden VJ, Sun L, Ye Z, Lich JD, Heise MT, Chen Z, Ting JP. Moore CB, et al. Among authors: duncan ja. Nature. 2008 Jan 31;451(7178):573-7. doi: 10.1038/nature06501. Epub 2008 Jan 16. Nature. 2008. PMID: 18200010

6

Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK.

Dan HC, Cooper MJ, Cogswell PC, Duncan JA, Ting JP, Baldwin AS. Dan HC, et al. Among authors: duncan ja. Genes Dev. 2008 Jun 1;22(11):1490-500. doi: 10.1101/gad.1662308. Genes Dev. 2008. PMID: 18519641 Free PMC article.

7

Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome.

Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP. Duncan JA, et al. J Immunol. 2009 May 15;182(10):6460-9. doi: 10.4049/jimmunol.0802696. J Immunol. 2009. PMID: 19414800 Free PMC article.

8

NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.

Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, Ting JP. Willingham SB, et al. Among authors: duncan ja. J Immunol. 2009 Aug 1;183(3):2008-15. doi: 10.4049/jimmunol.0900138. Epub 2009 Jul 8. J Immunol. 2009. PMID: 19587006 Free PMC article.

9

Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells.

Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, McElvania-Tekippe E, Ting JP, Duncan JA. Craven RR, et al. Among authors: duncan ja. PLoS One. 2009 Oct 14;4(10):e7446. doi: 10.1371/journal.pone.0007446. PLoS One. 2009. PMID: 19826485 Free PMC article.

10

How the noninflammasome NLRs function in the innate immune system.

Ting JP, Duncan JA, Lei Y. Ting JP, et al. Among authors: duncan ja. Science. 2010 Jan 15;327(5963):286-90. doi: 10.1126/science.1184004. Science. 2010. PMID: 20075243 Free PMC article. Review.

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