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GI-4000 in KRAS mutant cancers.
Shahda S, O'Neil B. Shahda S, et al. Expert Opin Investig Drugs. 2014 Feb;23(2):273-8. doi: 10.1517/13543784.2014.876408. Epub 2013 Dec 30. Expert Opin Investig Drugs. 2014. PMID: 24372276 Review.
A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer.
O'Neil BH, Scott AJ, Ma WW, Cohen SJ, Aisner DL, Menter AR, Tejani MA, Cho JK, Granfortuna J, Coveler L, Olowokure OO, Baranda JC, Cusnir M, Phillip P, Boles J, Nazemzadeh R, Rarick M, Cohen DJ, Radford J, Fehrenbacher L, Bajaj R, Bathini V, Fanta P, Berlin J, McRee AJ, Maguire R, Wilhelm F, Maniar M, Jimeno A, Gomes CL, Messersmith WA. O'Neil BH, et al. Ann Oncol. 2015 Sep;26(9):1923-1929. doi: 10.1093/annonc/mdv264. Epub 2015 Jun 19. Ann Oncol. 2015. PMID: 26091808 Free PMC article. Clinical Trial.
Clinical benefit of a precision medicine based approach for guiding treatment of refractory cancers.
Radovich M, Kiel PJ, Nance SM, Niland EE, Parsley ME, Ferguson ME, Jiang G, Ammakkanavar NR, Einhorn LH, Cheng L, Nassiri M, Davidson DD, Rushing DA, Loehrer PJ, Pili R, Hanna N, Callaghan JT, Skaar TC, Helft PR, Shahda S, O'Neil BH, Schneider BP. Radovich M, et al. Oncotarget. 2016 Aug 30;7(35):56491-56500. doi: 10.18632/oncotarget.10606. Oncotarget. 2016. PMID: 27447854 Free PMC article.
464 results