Minchom A - Search Results

1

A study of PD-L1 expression in KRAS mutant non-small cell lung cancer cell lines exposed to relevant targeted treatments.

Minchom A, Thavasu P, Ahmad Z, Stewart A, Georgiou A, O'Brien MER, Popat S, Bhosle J, Yap TA, de Bono J, Banerji U. Minchom A, et al. PLoS One. 2017 Oct 5;12(10):e0186106. doi: 10.1371/journal.pone.0186106. eCollection 2017. PLoS One. 2017. PMID: 28982179 Free PMC article.

2

The diagnosis and treatment of brain metastases in EGFR mutant lung cancer.

Minchom A, Yu KC, Bhosle J, O'Brien M. Minchom A, et al. CNS Oncol. 2014 May;3(3):209-17. doi: 10.2217/cns.14.19. CNS Oncol. 2014. PMID: 25055129 Free PMC article. Review.

3

An unblinded, randomised phase II study of platinum-based chemotherapy with vitamin B12 and folic acid supplementation in the treatment of lung cancer with plasma homocysteine blood levels as a biomarker of severe neutropenic toxicity.

Minchom AR, Saksornchai K, Bhosle J, Gunapala R, Puglisi M, Lu SK, Nimako K, Coward J, Yu KC, Bordi P, Popat S, O'Brien ME. Minchom AR, et al. BMJ Open Respir Res. 2014 Dec 11;1(1):e000061. doi: 10.1136/bmjresp-2014-000061. eCollection 2014. BMJ Open Respir Res. 2014. PMID: 25553247 Free PMC article.

4

A phase 1b trial of the combination of an all-oral regimen of capecitabine and erlotinib in advanced non-small cell lung cancer in Caucasian patients.

Kumar R, Lu SK, Minchom A, Sharp A, Davidson M, Gunapala R, Yap TA, Bhosle J, Popat S, O'Brien ME. Kumar R, et al. Among authors: minchom a. Cancer Chemother Pharmacol. 2016 Feb;77(2):375-83. doi: 10.1007/s00280-015-2950-1. Epub 2015 Dec 26. Cancer Chemother Pharmacol. 2016. PMID: 26706729

5

Characterisation of the Phosphatidylinositol 3-Kinase Pathway in Non-Small Cell Lung Cancer Cells Isolated from Pleural Effusions.

Puglisi M, Stewart A, Thavasu P, Frow M, Carreira S, Minchom A, Punwani R, Bhosle J, Popat S, Ratoff J, de Bono J, Yap TA, O''Brien M, Banerji U. Puglisi M, et al. Among authors: minchom a. Oncology. 2016;90(5):280-8. doi: 10.1159/000444928. Epub 2016 Apr 16. Oncology. 2016. PMID: 27082424

6

A randomised study comparing the effectiveness of acupuncture or morphine versus the combination for the relief of dyspnoea in patients with advanced non-small cell lung cancer and mesothelioma.

Minchom A, Punwani R, Filshie J, Bhosle J, Nimako K, Myerson J, Gunapala R, Popat S, O'Brien ME. Minchom A, et al. Eur J Cancer. 2016 Jul;61:102-10. doi: 10.1016/j.ejca.2016.03.078. Epub 2016 May 6. Eur J Cancer. 2016. PMID: 27156228 Clinical Trial.

7

Multidisciplinary interventions in a specialist Drug Development Unit to improve family history documentation and onward referral of patients with advanced cancer to cancer genetics services.

Moss CA, Cojocaru E, Hanwell J, Ward S, Xu W, van Zyl M, O'Leary L, de Bono JS, Banerji U, Kaye SB, Minchom A, George AJ, Lopez J, McVeigh TP. Moss CA, et al. Among authors: minchom a. Eur J Cancer. 2019 Jun;114:97-106. doi: 10.1016/j.ejca.2019.04.009. Epub 2019 May 16. Eur J Cancer. 2019. PMID: 31078974

8

Comment on 'Randomised phase 2 study of pembrolizumab plus CC-486 versus pembrolizumab plus placebo in patients with previously treated advanced non-small cell lung cancer'-No support for de-escalation of immunotherapy.

Georgiou A, Minchom A, O'Brien M. Georgiou A, et al. Among authors: minchom a. Eur J Cancer. 2019 Jul;115:24-26. doi: 10.1016/j.ejca.2019.04.011. Epub 2019 May 10. Eur J Cancer. 2019. PMID: 31082689 No abstract available.

9

Differences in Signaling Patterns on PI3K Inhibition Reveal Context Specificity in KRAS-Mutant Cancers.

Stewart A, Coker EA, Pölsterl S, Georgiou A, Minchom AR, Carreira S, Cunningham D, O'Brien ME, Raynaud FI, de Bono JS, Al-Lazikani B, Banerji U. Stewart A, et al. Among authors: minchom ar. Mol Cancer Ther. 2019 Aug;18(8):1396-1404. doi: 10.1158/1535-7163.MCT-18-0727. Epub 2019 Jul 1. Mol Cancer Ther. 2019. PMID: 31262731 Free PMC article.

10

Challenging the recalcitrant disease-developing molecularly driven treatments for small cell lung cancer.

Mak DWS, Li S, Minchom A. Mak DWS, et al. Among authors: minchom a. Eur J Cancer. 2019 Sep;119:132-150. doi: 10.1016/j.ejca.2019.04.037. Epub 2019 Aug 21. Eur J Cancer. 2019. PMID: 31445197 Review.

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