Chua BT - Search Results

1

Primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 encodes a novel Rac1/Cdc42 GAP that modulates cell migration and blood-aqueous barrier function.

Lee MC, Shei W, Chan AS, Chua BT, Goh SR, Chong YF, Hilmy MH, Nongpiur ME, Baskaran M, Khor CC, Aung T, Hunziker W, Vithana EN. Lee MC, et al. Among authors: chua bt. Hum Mol Genet. 2017 Oct 15;26(20):4011-4027. doi: 10.1093/hmg/ddx292. Hum Mol Genet. 2017. PMID: 29016860

2

Bosutinib inhibits migration and invasion via ACK1 in KRAS mutant non-small cell lung cancer.

Tan DS, Haaland B, Gan JM, Tham SC, Sinha I, Tan EH, Lim KH, Takano A, Krisna SS, Thu MM, Liew HP, Ullrich A, Lim WT, Chua BT. Tan DS, et al. Among authors: chua bt. Mol Cancer. 2014 Jan 24;13:13. doi: 10.1186/1476-4598-13-13. Mol Cancer. 2014. PMID: 24461128 Free PMC article.

3

Klotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth factor receptor-4 signaling in hepatocellular carcinoma.

Poh W, Wong W, Ong H, Aung MO, Lim SG, Chua BT, Ho HK. Poh W, et al. Among authors: chua bt. Mol Cancer. 2012 Mar 23;11:14. doi: 10.1186/1476-4598-11-14. Mol Cancer. 2012. PMID: 22439738 Free PMC article.

4

Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma.

Tan DSW, Chong FT, Leong HS, Toh SY, Lau DP, Kwang XL, Zhang X, Sundaram GM, Tan GS, Chang MM, Chua BT, Lim WT, Tan EH, Ang MK, Lim TKH, Sampath P, Chowbay B, Skanderup AJ, DasGupta R, Iyer NG. Tan DSW, et al. Among authors: chua bt. Nat Med. 2017 Oct;23(10):1167-1175. doi: 10.1038/nm.4401. Epub 2017 Sep 18. Nat Med. 2017. PMID: 28920960

5

Overexpression of Tyro3 and its implications on hepatocellular carcinoma progression.

Duan Y, Wong W, Chua SC, Wee HL, Lim SG, Chua BT, Ho HK. Duan Y, et al. Among authors: chua bt. Int J Oncol. 2016 Jan;48(1):358-66. doi: 10.3892/ijo.2015.3244. Epub 2015 Nov 13. Int J Oncol. 2016. PMID: 26573872

6

Benzylidene-indolinones are effective as multi-targeted kinase inhibitor therapeutics against hepatocellular carcinoma.

Ho HK, Chua BT, Wong W, Lim KS, Teo V, Ong HT, Chen X, Zhang W, Hui KM, Go ML, Ullrich A. Ho HK, et al. Among authors: chua bt. Mol Oncol. 2014 Oct;8(7):1266-77. doi: 10.1016/j.molonc.2014.04.008. Epub 2014 May 2. Mol Oncol. 2014. PMID: 24839937 Free PMC article.

7

Current strategies for inhibiting FGFR activities in clinical applications: opportunities, challenges and toxicological considerations.

Ho HK, Yeo AH, Kang TS, Chua BT. Ho HK, et al. Among authors: chua bt. Drug Discov Today. 2014 Jan;19(1):51-62. doi: 10.1016/j.drudis.2013.07.021. Epub 2013 Aug 6. Drug Discov Today. 2014. PMID: 23932951 Review.

8

Developing FGFR4 inhibitors as potential anti-cancer agents via in silico design, supported by in vitro and cell-based testing.

Ho HK, Németh G, Ng YR, Pang E, Szántai-Kis C, Zsákai L, Breza N, Greff Z, Horváth Z, Pató J, Szabadkai I, Szokol B, Baska F, Őrfî L, Ullrich A, Kéri G, Chua BT. Ho HK, et al. Among authors: chua bt. Curr Med Chem. 2013;20(10):1203-17. doi: 10.2174/0929867311320100001. Curr Med Chem. 2013. PMID: 23409720

9

Regulation of Akt(ser473) phosphorylation by choline kinase in breast carcinoma cells.

Chua BT, Gallego-Ortega D, Ramirez de Molina A, Ullrich A, Lacal JC, Downward J. Chua BT, et al. Mol Cancer. 2009 Dec 31;8:131. doi: 10.1186/1476-4598-8-131. Mol Cancer. 2009. PMID: 20042122 Free PMC article.

10

Somatic mutation in the ACK1 ubiquitin association domain enhances oncogenic signaling through EGFR regulation in renal cancer derived cells.

Chua BT, Lim SJ, Tham SC, Poh WJ, Ullrich A. Chua BT, et al. Mol Oncol. 2010 Aug;4(4):323-34. doi: 10.1016/j.molonc.2010.03.001. Epub 2010 Mar 19. Mol Oncol. 2010. PMID: 20359967 Free PMC article.

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