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Using hydrogen sulfide to design and develop drugs.
Calderone V, Martelli A, Testai L, Citi V, Breschi MC. Calderone V, et al. Among authors: citi v. Expert Opin Drug Discov. 2016;11(2):163-75. doi: 10.1517/17460441.2016.1122590. Epub 2015 Dec 19. Expert Opin Drug Discov. 2016. PMID: 26593865 Review.
The novel H2S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoKATP channels and reduction of oxidative stress.
Testai L, Marino A, Piano I, Brancaleone V, Tomita K, Di Cesare Mannelli L, Martelli A, Citi V, Breschi MC, Levi R, Gargini C, Bucci M, Cirino G, Ghelardini C, Calderone V. Testai L, et al. Among authors: citi v. Pharmacol Res. 2016 Nov;113(Pt A):290-299. doi: 10.1016/j.phrs.2016.09.006. Epub 2016 Sep 9. Pharmacol Res. 2016. PMID: 27616550
70 results