Cell surface CD63 increased by up-regulated polylactosamine modification sensitizes human melanoma cells to the BRAF inhibitor PLX4032.
Kudo K, Yoneda A, Sakiyama D, Kojima K, Miyaji T, Yamazaki M, Yaita S, Hyodo T, Satow R, Fukami K.
Kudo K, et al. Among authors: fukami k.
FASEB J. 2019 Mar;33(3):3851-3869. doi: 10.1096/fj.201800664RR. Epub 2018 Dec 3.
FASEB J. 2019.
PMID: 30508500
Our study shows the potential of CD63 to sensitize melanoma cells to PLX4032 and to reduce the proliferation of PLX4032-resistant cells.-Kudo, K., Yoneda, A., Sakiyama, D., Kojima, K., Miyaji, T., Yamazaki, M., Yaita, S., Hyodo, T., Satow, R., Fukami, K …
Our study shows the potential of CD63 to sensitize melanoma cells to PLX4032 and to reduce the proliferation of PLX4032-resistant cells.-Kud …