Sharma M - Search Results

1

Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines.

France SP, Aleku GA, Sharma M, Mangas-Sanchez J, Howard RM, Steflik J, Kumar R, Adams RW, Slabu I, Crook R, Grogan G, Wallace TW, Turner NJ. France SP, et al. Among authors: sharma m. Angew Chem Int Ed Engl. 2017 Dec 4;56(49):15589-15593. doi: 10.1002/anie.201708453. Epub 2017 Nov 7. Angew Chem Int Ed Engl. 2017. PMID: 29024400 Free article.

2

Imine reductases (IREDs).

Mangas-Sanchez J, France SP, Montgomery SL, Aleku GA, Man H, Sharma M, Ramsden JI, Grogan G, Turner NJ. Mangas-Sanchez J, et al. Among authors: sharma m. Curr Opin Chem Biol. 2017 Apr;37:19-25. doi: 10.1016/j.cbpa.2016.11.022. Epub 2016 Dec 27. Curr Opin Chem Biol. 2017. PMID: 28038349 Free article. Review.

3

A reductive aminase from Aspergillus oryzae.

Aleku GA, France SP, Man H, Mangas-Sanchez J, Montgomery SL, Sharma M, Leipold F, Hussain S, Grogan G, Turner NJ. Aleku GA, et al. Among authors: sharma m. Nat Chem. 2017 Oct;9(10):961-969. doi: 10.1038/nchem.2782. Epub 2017 May 29. Nat Chem. 2017. PMID: 28937665

4

New imine-reducing enzymes from β-hydroxyacid dehydrogenases by single amino acid substitutions.

Lenz M, Fademrecht S, Sharma M, Pleiss J, Grogan G, Nestl BM. Lenz M, et al. Among authors: sharma m. Protein Eng Des Sel. 2018 Apr 1;31(4):109-120. doi: 10.1093/protein/gzy006. Protein Eng Des Sel. 2018. PMID: 29733377

5

NAD(P)H-Dependent Dehydrogenases for the Asymmetric Reductive Amination of Ketones: Structure, Mechanism, Evolution and Application.

Sharma M, Mangas-Sanchez J, Turner NJ, Grogan G. Sharma M, et al. Adv Synth Catal. 2017 Jun 19;359(12):2011-2025. doi: 10.1002/adsc.201700356. Epub 2017 May 11. Adv Synth Catal. 2017. PMID: 30008635 Free PMC article. Review.

6

Characterization and structure-guided engineering of the novel versatile terpene monooxygenase CYP109Q5 from Chondromyces apiculatus DSM436.

Klenk JM, Dubiel P, Sharma M, Grogan G, Hauer B. Klenk JM, et al. Among authors: sharma m. Microb Biotechnol. 2019 Mar;12(2):377-391. doi: 10.1111/1751-7915.13354. Epub 2018 Dec 27. Microb Biotechnol. 2019. PMID: 30592153 Free PMC article.

7

Identification and characterization of cytochrome P450 1232A24 and 1232F1 from Arthrobacter sp. and their role in the metabolic pathway of papaverine.

Klenk JM, Fischer MP, Dubiel P, Sharma M, Rowlinson B, Grogan G, Hauer B. Klenk JM, et al. Among authors: sharma m. J Biochem. 2019 Jul 1;166(1):51-66. doi: 10.1093/jb/mvz010. J Biochem. 2019. PMID: 30759214 Free article.

8

Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions.

Eger E, Simon A, Sharma M, Yang S, Breukelaar WB, Grogan G, Houk KN, Kroutil W. Eger E, et al. Among authors: sharma m. J Am Chem Soc. 2020 Jan 15;142(2):792-800. doi: 10.1021/jacs.9b08704. Epub 2020 Jan 7. J Am Chem Soc. 2020. PMID: 31909617 Free PMC article.

9

Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases.

Mangas-Sanchez J, Sharma M, Cosgrove SC, Ramsden JI, Marshall JR, Thorpe TW, Palmer RB, Grogan G, Turner NJ. Mangas-Sanchez J, et al. Among authors: sharma m. Chem Sci. 2020 May 5;11(19):5052-5057. doi: 10.1039/d0sc02253e. Chem Sci. 2020. PMID: 34122962 Free PMC article.

10

Inverting the Stereoselectivity of an NADH-Dependent Imine-Reductase Variant.

Stockinger P, Borlinghaus N, Sharma M, Aberle B, Grogan G, Pleiss J, Nestl BM. Stockinger P, et al. Among authors: sharma m. ChemCatChem. 2021 Dec 15;13(24):5210-5215. doi: 10.1002/cctc.202101057. Epub 2021 Oct 22. ChemCatChem. 2021. PMID: 35873105 Free PMC article.

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