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Design, synthesis, and structure-activity relationship of novel LSD1 inhibitors based on pyrimidine-thiourea hybrids as potent, orally active antitumor agents.
Ma LY, Zheng YC, Wang SQ, Wang B, Wang ZR, Pang LP, Zhang M, Wang JW, Ding L, Li J, Wang C, Hu B, Liu Y, Zhang XD, Wang JJ, Wang ZJ, Zhao W, Liu HM. Ma LY, et al. Among authors: wang sq, wang jw, wang jj, wang zj, wang zr, wang c, wang b. J Med Chem. 2015 Feb 26;58(4):1705-16. doi: 10.1021/acs.jmedchem.5b00037. Epub 2015 Feb 6. J Med Chem. 2015. PMID: 25610955
Sulfonyl-containing phenyl-pyrrolyl pentane analogues: Novel non-secosteroidal vitamin D receptor modulators with favorable physicochemical properties, pharmacokinetic properties and anti-tumor activity.
Kang ZS, Wang C, Han XL, Wang B, Yuan HL, Hou SY, Hao MX, Du JJ, Li YY, Zhou AW, Zhang C. Kang ZS, et al. Among authors: wang c, wang b. Eur J Med Chem. 2018 Sep 5;157:1174-1191. doi: 10.1016/j.ejmech.2018.08.085. Epub 2018 Aug 31. Eur J Med Chem. 2018. PMID: 30193216
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