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Page 1
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.
Mack SC, Pajtler KW, Chavez L, Okonechnikov K, Bertrand KC, Wang X, Erkek S, Federation A, Song A, Lee C, Wang X, McDonald L, Morrow JJ, Saiakhova A, Sin-Chan P, Wu Q, Michaelraj KA, Miller TE, Hubert CG, Ryzhova M, Garzia L, Donovan L, Dombrowski S, Factor DC, Luu B, Valentim CLL, Gimple RC, Morton A, Kim L, Prager BC, Lee JJY, Wu X, Zuccaro J, Thompson Y, Holgado BL, Reimand J, Ke SQ, Tropper A, Lai S, Vijayarajah S, Doan S, Mahadev V, Miñan AF, Gröbner SN, Lienhard M, Zapatka M, Huang Z, Aldape KD, Carcaboso AM, Houghton PJ, Keir ST, Milde T, Witt H, Li Y, Li CJ, Bian XW, Jones DTW, Scott I, Singh SK, Huang A, Dirks PB, Bouffet E, Bradner JE, Ramaswamy V, Jabado N, Rutka JT, Northcott PA, Lupien M, Lichter P, Korshunov A, Scacheri PC, Pfister SM, Kool M, Taylor MD, Rich JN. Mack SC, et al. Among authors: valentim cll. Nature. 2018 Jan 4;553(7686):101-105. doi: 10.1038/nature25169. Epub 2017 Dec 20. Nature. 2018. PMID: 29258295 Free PMC article.
Targeting glioma stem cells through combined BMI1 and EZH2 inhibition.
Jin X, Kim LJY, Wu Q, Wallace LC, Prager BC, Sanvoranart T, Gimple RC, Wang X, Mack SC, Miller TE, Huang P, Valentim CL, Zhou QG, Barnholtz-Sloan JS, Bao S, Sloan AE, Rich JN. Jin X, et al. Among authors: valentim cl. Nat Med. 2017 Nov;23(11):1352-1361. doi: 10.1038/nm.4415. Epub 2017 Oct 9. Nat Med. 2017. PMID: 29035367 Free PMC article.
FOXD1-ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells.
Cheng P, Wang J, Waghmare I, Sartini S, Coviello V, Zhang Z, Kim SH, Mohyeldin A, Pavlyukov MS, Minata M, Valentim CL, Chhipa RR, Bhat KP, Dasgupta B, La Motta C, Kango-Singh M, Nakano I. Cheng P, et al. Among authors: valentim cl. Cancer Res. 2016 Dec 15;76(24):7219-7230. doi: 10.1158/0008-5472.CAN-15-2860. Epub 2016 Aug 28. Cancer Res. 2016. PMID: 27569208 Free PMC article.
Cancer stem cells in glioblastoma.
Lathia JD, Mack SC, Mulkearns-Hubert EE, Valentim CL, Rich JN. Lathia JD, et al. Among authors: valentim cl. Genes Dev. 2015 Jun 15;29(12):1203-17. doi: 10.1101/gad.261982.115. Genes Dev. 2015. PMID: 26109046 Free PMC article. Review.
Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites.
Valentim CL, Cioli D, Chevalier FD, Cao X, Taylor AB, Holloway SP, Pica-Mattoccia L, Guidi A, Basso A, Tsai IJ, Berriman M, Carvalho-Queiroz C, Almeida M, Aguilar H, Frantz DE, Hart PJ, LoVerde PT, Anderson TJ. Valentim CL, et al. Science. 2013 Dec 13;342(6164):1385-9. doi: 10.1126/science.1243106. Epub 2013 Nov 21. Science. 2013. PMID: 24263136 Free PMC article.
Genomic linkage map of the human blood fluke Schistosoma mansoni.
Criscione CD, Valentim CL, Hirai H, LoVerde PT, Anderson TJ. Criscione CD, et al. Among authors: valentim cl. Genome Biol. 2009;10(6):R71. doi: 10.1186/gb-2009-10-6-r71. Epub 2009 Jun 30. Genome Biol. 2009. PMID: 19566921 Free PMC article.