Luesch H - Search Results

1

Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors.

Cai W, Chen QY, Dang LH, Luesch H. Cai W, et al. Among authors: luesch h. ACS Med Chem Lett. 2017 Sep 18;8(10):1007-1012. doi: 10.1021/acsmedchemlett.7b00192. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057042 Free PMC article.

2

Combination therapy targeting cancer metabolism.

Wenger JB, Chun SY, Dang DT, Luesch H, Dang LH. Wenger JB, et al. Among authors: luesch h. Med Hypotheses. 2011 Feb;76(2):169-72. doi: 10.1016/j.mehy.2010.09.008. Epub 2010 Oct 13. Med Hypotheses. 2011. PMID: 20947261 Free PMC article. Review.

3

Can we develop effective combination antiangiogenic therapy for patients with hepatocellular carcinoma?

Wenger JB, Santos N, Liu Y, Dallas J, Subbiah S, Hochwald S, Huang EH, Dang DT, Allegra CJ, Luesch H, Dang LH. Wenger JB, et al. Among authors: luesch h. Oncol Rev. 2011 Sep;5(3):177-184. doi: 10.1007/s12156-011-0082-3. Oncol Rev. 2011. PMID: 21949574 Free PMC article.

4

Systematic Chemical Mutagenesis Identifies a Potent Novel Apratoxin A/E Hybrid with Improved in Vivo Antitumor Activity.

Chen QY, Liu Y, Luesch H. Chen QY, et al. Among authors: luesch h. ACS Med Chem Lett. 2011 Nov 10;2(11):861-865. doi: 10.1021/ml200176m. Epub 2011 Aug 31. ACS Med Chem Lett. 2011. PMID: 22081789 Free PMC article.

5

Combination therapy for renal cell cancer: what are possible options?

Santos N, Wenger JB, Havre P, Liu Y, Dagan R, Imanirad I, Ivey AM, Zlotecki RA, Algood CB, Gilbert SM, Allegra CJ, Okunieff P, Vieweg J, Dang NH, Luesch H, Dang LH. Santos N, et al. Among authors: luesch h. Oncology. 2011;81(3-4):220-9. doi: 10.1159/000333470. Epub 2011 Nov 12. Oncology. 2011. PMID: 22085914 Free PMC article. Review.

6

Cyanobacterial peptides as a prototype for the design of potent β-secretase inhibitors and the development of selective chemical probes for other aspartic proteases.

Liu Y, Zhang W, Li L, Salvador LA, Chen T, Chen W, Felsenstein KM, Ladd TB, Price AR, Golde TE, He J, Xu Y, Li Y, Luesch H. Liu Y, et al. Among authors: luesch h. J Med Chem. 2012 Dec 13;55(23):10749-65. doi: 10.1021/jm301630s. Epub 2012 Nov 26. J Med Chem. 2012. PMID: 23181502

7

Largazole pharmacokinetics in rats by LC-MS/MS.

Yu M, Salvador LA, Sy SK, Tang Y, Singh RS, Chen QY, Liu Y, Hong J, Derendorf H, Luesch H. Yu M, et al. Among authors: luesch h. Mar Drugs. 2014 Mar 20;12(3):1623-40. doi: 10.3390/md12031623. Mar Drugs. 2014. PMID: 24658499 Free PMC article.

8

Improved total synthesis and biological evaluation of potent apratoxin S4 based anticancer agents with differential stability and further enhanced activity.

Chen QY, Liu Y, Cai W, Luesch H. Chen QY, et al. Among authors: luesch h. J Med Chem. 2014 Apr 10;57(7):3011-29. doi: 10.1021/jm4019965. Epub 2014 Mar 24. J Med Chem. 2014. PMID: 24660812 Free PMC article.

9

Evaluation of class I HDAC isoform selectivity of largazole analogues.

Kim B, Park H, Salvador LA, Serrano PE, Kwan JC, Zeller SL, Chen QY, Ryu S, Liu Y, Byeon S, Luesch H, Hong J. Kim B, et al. Among authors: luesch h. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3728-31. doi: 10.1016/j.bmcl.2014.07.006. Epub 2014 Jul 9. Bioorg Med Chem Lett. 2014. PMID: 25070421 Free PMC article.

10

Modulation of Activity Profiles for Largazole-Based HDAC Inhibitors through Alteration of Prodrug Properties.

Salvador LA, Park H, Al-Awadhi FH, Liu Y, Kim B, Zeller SL, Chen QY, Hong J, Luesch H. Salvador LA, et al. Among authors: luesch h. ACS Med Chem Lett. 2014 Jul 7;5(8):905-10. doi: 10.1021/ml500170r. eCollection 2014 Aug 14. ACS Med Chem Lett. 2014. PMID: 25147612 Free PMC article.

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