Iyer CC - Search Results

1

HuD and the Survival Motor Neuron Protein Interact in Motoneurons and Are Essential for Motoneuron Development, Function, and mRNA Regulation.

Hao le T, Duy PQ, An M, Talbot J, Iyer CC, Wolman M, Beattie CE. Hao le T, et al. Among authors: iyer cc. J Neurosci. 2017 Nov 29;37(48):11559-11571. doi: 10.1523/JNEUROSCI.1528-17.2017. Epub 2017 Oct 23. J Neurosci. 2017. PMID: 29061699 Free PMC article.

2

Low levels of Survival Motor Neuron protein are sufficient for normal muscle function in the SMNΔ7 mouse model of SMA.

Iyer CC, McGovern VL, Murray JD, Gombash SE, Zaworski PG, Foust KD, Janssen PM, Burghes AH. Iyer CC, et al. Hum Mol Genet. 2015 Nov 1;24(21):6160-73. doi: 10.1093/hmg/ddv332. Epub 2015 Aug 13. Hum Mol Genet. 2015. PMID: 26276812 Free PMC article.

3

SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNΔ7 mouse model of SMA.

McGovern VL, Iyer CC, Arnold WD, Gombash SE, Zaworski PG, Blatnik AJ 3rd, Foust KD, Burghes AH. McGovern VL, et al. Among authors: iyer cc. Hum Mol Genet. 2015 Oct 1;24(19):5524-41. doi: 10.1093/hmg/ddv283. Epub 2015 Jul 23. Hum Mol Genet. 2015. PMID: 26206889 Free PMC article.

4

SMN deficiency disrupts gastrointestinal and enteric nervous system function in mice.

Gombash SE, Cowley CJ, Fitzgerald JA, Iyer CC, Fried D, McGovern VL, Williams KC, Burghes AH, Christofi FL, Gulbransen BD, Foust KD. Gombash SE, et al. Among authors: iyer cc. Hum Mol Genet. 2015 Jul 1;24(13):3847-60. doi: 10.1093/hmg/ddv127. Epub 2015 Apr 9. Hum Mol Genet. 2015. PMID: 25859009 Free PMC article.

5

SMN Blood Levels in a Porcine Model of Spinal Muscular Atrophy.

Iyer CC, Wang X, Renusch SR, Duque SI, Wehr AM, Mo XM, McGovern VL, Arnold WD, Burghes AH, Kolb SJ. Iyer CC, et al. J Neuromuscul Dis. 2017;4(1):59-66. doi: 10.3233/JND-170209. J Neuromuscul Dis. 2017. PMID: 28269795 Free PMC article.

6

Conditional deletion of SMN in cell culture identifies functional SMN alleles.

Blatnik AJ, McGovern VL, Le TT, Iyer CC, Kaspar BK, Burghes AHM. Blatnik AJ, et al. Among authors: iyer cc. Hum Mol Genet. 2020 Nov 1;29(21):3477-3492. doi: 10.1093/hmg/ddaa229. Epub 2020 Oct 19. Hum Mol Genet. 2020. PMID: 33075805 Free PMC article.

7

Intragenic complementation of amino and carboxy terminal SMN missense mutations can rescue Smn null mice.

McGovern VL, Kray KM, Arnold WD, Duque SI, Iyer CC, Massoni-Laporte A, Workman E, Patel A, Battle DJ, Burghes AHM. McGovern VL, et al. Among authors: iyer cc. Hum Mol Genet. 2020 Nov 1;29(21):3493-3503. doi: 10.1093/hmg/ddaa235. Hum Mol Genet. 2020. PMID: 33084884 Free PMC article.

8

Deletion of atrophy enhancing genes fails to ameliorate the phenotype in a mouse model of spinal muscular atrophy.

Iyer CC, McGovern VL, Wise DO, Glass DJ, Burghes AH. Iyer CC, et al. Neuromuscul Disord. 2014 May;24(5):436-44. doi: 10.1016/j.nmd.2014.02.007. Epub 2014 Feb 25. Neuromuscul Disord. 2014. PMID: 24656734 Free PMC article.

9

Mild SMN missense alleles are only functional in the presence of SMN2 in mammals.

Iyer CC, Corlett KM, Massoni-Laporte A, Duque SI, Madabusi N, Tisdale S, McGovern VL, Le TT, Zaworski PG, Arnold WD, Pellizzoni L, Burghes AHM. Iyer CC, et al. Hum Mol Genet. 2018 Oct 1;27(19):3404-3416. doi: 10.1093/hmg/ddy251. Hum Mol Genet. 2018. PMID: 29982416 Free PMC article.

10

Normalization of Patient-Identified Plasma Biomarkers in SMNΔ7 Mice following Postnatal SMN Restoration.

Arnold WD, Duque S, Iyer CC, Zaworski P, McGovern VL, Taylor SJ, von Herrmann KM, Kobayashi DT, Chen KS, Kolb SJ, Paushkin SV, Burghes AH. Arnold WD, et al. Among authors: iyer cc. PLoS One. 2016 Dec 1;11(12):e0167077. doi: 10.1371/journal.pone.0167077. eCollection 2016. PLoS One. 2016. PMID: 27907033 Free PMC article.

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