Nicolaou KC - Search Results

1

Enantioselective Total Synthesis of Antibiotic CJ-16,264, Synthesis and Biological Evaluation of Designed Analogues, and Discovery of Highly Potent and Simpler Antibacterial Agents.

Nicolaou KC, Pulukuri KK, Rigol S, Buchman M, Shah AA, Cen N, McCurry MD, Beabout K, Shamoo Y. Nicolaou KC, et al. J Am Chem Soc. 2017 Nov 8;139(44):15868-15877. doi: 10.1021/jacs.7b08749. Epub 2017 Oct 24. J Am Chem Soc. 2017. PMID: 29064688 Free PMC article.

2

Total synthesis of viridicatumtoxin B and analogues thereof: strategy evolution, structural revision, and biological evaluation.

Nicolaou KC, Hale CR, Nilewski C, Ioannidou HA, ElMarrouni A, Nilewski LG, Beabout K, Wang TT, Shamoo Y. Nicolaou KC, et al. J Am Chem Soc. 2014 Aug 27;136(34):12137-60. doi: 10.1021/ja506472u. Epub 2014 Aug 15. J Am Chem Soc. 2014. PMID: 25317739 Free PMC article.

3

Total Synthesis and Structural Revision of Antibiotic CJ-16,264.

Nicolaou KC, Shah AA, Korman H, Khan T, Shi L, Worawalai W, Theodorakis EA. Nicolaou KC, et al. Angew Chem Int Ed Engl. 2015 Aug 3;54(32):9203-8. doi: 10.1002/anie.201504337. Epub 2015 Jun 19. Angew Chem Int Ed Engl. 2015. PMID: 26096055 Free PMC article.

4

Synthesis and Biological Investigation of Δ(12)-Prostaglandin J3 (Δ(12)-PGJ3) Analogues and Related Compounds.

Nicolaou KC, Pulukuri KK, Rigol S, Heretsch P, Yu R, Grove CI, Hale CR, ElMarrouni A, Fetz V, Brönstrup M, Aujay M, Sandoval J, Gavrilyuk J. Nicolaou KC, et al. J Am Chem Soc. 2016 May 25;138(20):6550-60. doi: 10.1021/jacs.6b02075. Epub 2016 May 12. J Am Chem Soc. 2016. PMID: 27171618

5

Streamlined Total Synthesis of Uncialamycin and Its Application to the Synthesis of Designed Analogues for Biological Investigations.

Nicolaou KC, Wang Y, Lu M, Mandal D, Pattanayak MR, Yu R, Shah AA, Chen JS, Zhang H, Crawford JJ, Pasunoori L, Poudel YB, Chowdari NS, Pan C, Nazeer A, Gangwar S, Vite G, Pitsinos EN. Nicolaou KC, et al. J Am Chem Soc. 2016 Jul 6;138(26):8235-46. doi: 10.1021/jacs.6b04339. Epub 2016 Jun 27. J Am Chem Soc. 2016. PMID: 27266267

6

Asymmetric Alkylation of Anthrones, Enantioselective Total Synthesis of (-)- and (+)-Viridicatumtoxins B and Analogues Thereof: Absolute Configuration and Potent Antibacterial Agents.

Nicolaou KC, Liu G, Beabout K, McCurry MD, Shamoo Y. Nicolaou KC, et al. J Am Chem Soc. 2017 Mar 15;139(10):3736-3746. doi: 10.1021/jacs.6b12654. Epub 2017 Mar 3. J Am Chem Soc. 2017. PMID: 28256128 Free PMC article.

7

Experimental Evolution of Diverse Strains as a Method for the Determination of Biochemical Mechanisms of Action for Novel Pyrrolizidinone Antibiotics.

Beabout K, McCurry MD, Mehta H, Shah AA, Pulukuri KK, Rigol S, Wang Y, Nicolaou KC, Shamoo Y. Beabout K, et al. Among authors: nicolaou kc. ACS Infect Dis. 2017 Nov 10;3(11):854-865. doi: 10.1021/acsinfecdis.7b00135. Epub 2017 Sep 27. ACS Infect Dis. 2017. PMID: 28942642 Free PMC article.

8

Streamlined Total Synthesis of Trioxacarcins and Its Application to the Design, Synthesis, and Biological Evaluation of Analogues Thereof. Discovery of Simpler Designed and Potent Trioxacarcin Analogues.

Nicolaou KC, Chen P, Zhu S, Cai Q, Erande RD, Li R, Sun H, Pulukuri KK, Rigol S, Aujay M, Sandoval J, Gavrilyuk J. Nicolaou KC, et al. J Am Chem Soc. 2017 Nov 1;139(43):15467-15478. doi: 10.1021/jacs.7b08820. Epub 2017 Oct 20. J Am Chem Soc. 2017. PMID: 29052423

9

Total Syntheses of Disorazoles A₁ and B₁ and Full Structural Elucidation of Disorazole B₁.

Nicolaou KC, Bellavance G, Buchman M, Pulukuri KK. Nicolaou KC, et al. J Am Chem Soc. 2017 Nov 8;139(44):15636-15639. doi: 10.1021/jacs.7b09843. Epub 2017 Oct 24. J Am Chem Soc. 2017. PMID: 29064682

10

Short Total Synthesis of Δ¹²-Prostaglandin J₂ and Related Prostaglandins. Design, Synthesis, and Biological Evaluation of Macrocyclic Δ¹²-Prostaglandin J₂ Analogues.

Nicolaou KC, Pulukuri KK, Rigol S, Peitsinis Z, Yu R, Kishigami S, Cen N, Aujay M, Sandoval J, Zepeda N, Gavrilyuk J. Nicolaou KC, et al. J Org Chem. 2019 Jan 4;84(1):365-378. doi: 10.1021/acs.joc.8b03057. Epub 2018 Dec 20. J Org Chem. 2019. PMID: 30557504

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