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Transient Changes in Hepatic Physiology That Alter Bilirubin and Bile Acid Transport May Explain Elevations in Liver Chemistries Observed in Clinical Trials of GGF2 (Cimaglermin Alfa).
Mosedale M, Button D, Jackson JP, Freeman KM, Brouwer KR, Caggiano AO, Eisen A, Iaci JF, Parry TJ, Stanulis R, Srinivas M, Watkins PB. Mosedale M, et al. Among authors: button d. Toxicol Sci. 2018 Feb 1;161(2):401-411. doi: 10.1093/toxsci/kfx222. Toxicol Sci. 2018. PMID: 29069498
Refining Liver Safety Risk Assessment: Application of Mechanistic Modeling and Serum Biomarkers to Cimaglermin Alfa (GGF2) Clinical Trials.
Longo DM, Generaux GT, Howell BA, Siler SQ, Antoine DJ, Button D, Caggiano A, Eisen A, Iaci J, Stanulis R, Parry T, Mosedale M, Watkins PB. Longo DM, et al. Among authors: button d. Clin Pharmacol Ther. 2017 Dec;102(6):961-969. doi: 10.1002/cpt.711. Epub 2017 May 27. Clin Pharmacol Ther. 2017. PMID: 28419467 Free PMC article.
The Evaluation of Magnesium Chloride within a Polyethylene Glycol Formulation in a Porcine Model of Acute Spinal Cord Injury.
Streijger F, Lee JH, Manouchehri N, Okon EB, Tigchelaar S, Anderson LM, Dekaban GA, Rudko DA, Menon RS, Iaci JF, Button DC, Vecchione AM, Konovalov A, Sarmiere PD, Ung C, Caggiano AO, Kwon BK. Streijger F, et al. Among authors: button dc. J Neurotrauma. 2016 Dec 15;33(24):2202-2216. doi: 10.1089/neu.2016.4439. Epub 2016 Jun 1. J Neurotrauma. 2016. PMID: 27125815
Human Remyelination Promoting Antibody Stimulates Astrocytes Proliferation Through Modulation of the Sphingolipid Rheostat in Primary Rat Mixed Glial Cultures.
Grassi S, Giussani P, Prioni S, Button D, Cao J, Hakimi I, Sarmiere P, Srinivas M, Cabitta L, Sonnino S, Prinetti A. Grassi S, et al. Among authors: button d. Neurochem Res. 2019 Jun;44(6):1460-1474. doi: 10.1007/s11064-018-2701-x. Epub 2018 Dec 19. Neurochem Res. 2019. PMID: 30569280 Free article.
253 results