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Calcium signalling links MYC to NUAK1.
Monteverde T, Tait-Mulder J, Hedley A, Knight JR, Sansom OJ, Murphy DJ. Monteverde T, et al. Among authors: murphy dj. Oncogene. 2018 Feb 22;37(8):982-992. doi: 10.1038/onc.2017.394. Epub 2017 Nov 6. Oncogene. 2018. PMID: 29106388 Free PMC article.
MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance.
Farrell AS, Joly MM, Allen-Petersen BL, Worth PJ, Lanciault C, Sauer D, Link J, Pelz C, Heiser LM, Morton JP, Muthalagu N, Hoffman MT, Manning SL, Pratt ED, Kendsersky ND, Egbukichi N, Amery TS, Thoma MC, Jenny ZP, Rhim AD, Murphy DJ, Sansom OJ, Crawford HC, Sheppard BC, Sears RC. Farrell AS, et al. Among authors: murphy dj. Nat Commun. 2017 Nov 23;8(1):1728. doi: 10.1038/s41467-017-01967-6. Nat Commun. 2017. PMID: 29170413 Free PMC article.
Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress.
Port J, Muthalagu N, Raja M, Ceteci F, Monteverde T, Kruspig B, Hedley A, Kalna G, Lilla S, Neilson L, Brucoli M, Gyuraszova K, Tait-Mulder J, Mezna M, Svambaryte S, Bryson A, Sumpton D, McVie A, Nixon C, Drysdale M, Esumi H, Murray GI, Sansom OJ, Zanivan SR, Murphy DJ. Port J, et al. Among authors: murphy dj. Cancer Discov. 2018 May;8(5):632-647. doi: 10.1158/2159-8290.CD-17-0533. Epub 2018 Mar 2. Cancer Discov. 2018. PMID: 29500295 Free PMC article.
Is oxidative stress MYC's Achilles heel?
Muthalagu N, Murphy DJ. Muthalagu N, et al. Among authors: murphy dj. Cell Death Differ. 2018 Jul;25(7):1189-1190. doi: 10.1038/s41418-018-0117-4. Cell Death Differ. 2018. PMID: 29844569 Free PMC article. No abstract available.
The ERBB network facilitates KRAS-driven lung tumorigenesis.
Kruspig B, Monteverde T, Neidler S, Hock A, Kerr E, Nixon C, Clark W, Hedley A, Laing S, Coffelt SB, Le Quesne J, Dick C, Vousden KH, Martins CP, Murphy DJ. Kruspig B, et al. Among authors: murphy dj. Sci Transl Med. 2018 Jun 20;10(446):eaao2565. doi: 10.1126/scitranslmed.aao2565. Sci Transl Med. 2018. PMID: 29925636 Free PMC article.
739 results