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Optimized expression of the Starmerella bombicola lactone esterase in Pichia pastoris through temperature adaptation, codon-optimization and co-expression with HAC1.
De Waele S, Vandenberghe I, Laukens B, Planckaert S, Verweire S, Van Bogaert INA, Soetaert W, Devreese B, Ciesielska K. De Waele S, et al. Among authors: laukens b. Protein Expr Purif. 2018 Mar;143:62-70. doi: 10.1016/j.pep.2017.10.016. Epub 2017 Nov 4. Protein Expr Purif. 2018. PMID: 29108944
A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris.
Cerini F, Gaertner H, Madden K, Tolstorukov I, Brown S, Laukens B, Callewaert N, Harner JC, Oommen AM, Harms JT, Sump AR, Sealock RC, Peterson DJ, Johnson SK, Abramson SB, Meagher M, Offord R, Hartley O. Cerini F, et al. Among authors: laukens b. Protein Expr Purif. 2016 Mar;119:1-10. doi: 10.1016/j.pep.2015.10.011. Epub 2015 Oct 24. Protein Expr Purif. 2016. PMID: 26506568 Free PMC article.
Disruption of the SapM locus in Mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis.
Festjens N, Bogaert P, Batni A, Houthuys E, Plets E, Vanderschaeghe D, Laukens B, Asselbergh B, Parthoens E, De Rycke R, Willart MA, Jacques P, Elewaut D, Brouckaert P, Lambrecht BN, Huygen K, Callewaert N. Festjens N, et al. Among authors: laukens b. EMBO Mol Med. 2011 Apr;3(4):222-34. doi: 10.1002/emmm.201000125. Epub 2011 Feb 16. EMBO Mol Med. 2011. PMID: 21328541 Free PMC article.
15 results