Cobucci-Ponzano B - Search Results

1

N-Butyl-l-deoxynojirimycin (l-NBDNJ): Synthesis of an Allosteric Enhancer of α-Glucosidase Activity for the Treatment of Pompe Disease.

D'Alonzo D, De Fenza M, Porto C, Iacono R, Huebecker M, Cobucci-Ponzano B, Priestman DA, Platt F, Parenti G, Moracci M, Palumbo G, Guaragna A. D'Alonzo D, et al. J Med Chem. 2017 Dec 14;60(23):9462-9469. doi: 10.1021/acs.jmedchem.7b00646. Epub 2017 Nov 22. J Med Chem. 2017. PMID: 29112434

2

Identification and molecular characterization of the first alpha -xylosidase from an archaeon.

Moracci M, Cobucci Ponzano B, Trincone A, Fusco S, De Rosa M, van Der Oost J, Sensen CW, Charlebois RL, Rossi M. Moracci M, et al. J Biol Chem. 2000 Jul 21;275(29):22082-9. doi: 10.1074/jbc.M910392199. J Biol Chem. 2000. PMID: 10801892 Free article.

3

Ionic network at the C-terminus of the beta-glycosidase from the hyperthermophilic archaeon Sulfolobus solfataricus: Functional role in the quaternary structure thermal stabilization.

Cobucci-Ponzano B, Moracci M, Di Lauro B, Ciaramella M, D'Avino R, Rossi M. Cobucci-Ponzano B, et al. Proteins. 2002 Jul 1;48(1):98-106. doi: 10.1002/prot.10128. Proteins. 2002. PMID: 12012341

4

Identification of an archaeal alpha-L-fucosidase encoded by an interrupted gene. Production of a functional enzyme by mutations mimicking programmed -1 frameshifting.

Cobucci-Ponzano B, Trincone A, Giordano A, Rossi M, Moracci M. Cobucci-Ponzano B, et al. J Biol Chem. 2003 Apr 25;278(17):14622-31. doi: 10.1074/jbc.M211834200. Epub 2003 Feb 4. J Biol Chem. 2003. PMID: 12569098 Free article.

5

Identification of the catalytic nucleophile of the family 29 alpha-L-fucosidase from Sulfolobus solfataricus via chemical rescue of an inactive mutant.

Cobucci-Ponzano B, Trincone A, Giordano A, Rossi M, Moracci M. Cobucci-Ponzano B, et al. Biochemistry. 2003 Aug 19;42(32):9525-31. doi: 10.1021/bi035036t. Biochemistry. 2003. PMID: 12911294

6

Two-dimensional IR correlation spectroscopy of mutants of the beta-glycosidase from the hyperthermophilic archaeon Sulfolobus solfataricus identifies the mechanism of quaternary structure stabilization and unravels the sequence of thermal unfolding events.

Ausili A, Di Lauro B, Cobucci-Ponzano B, Bertoli E, Scirè A, Rossi M, Tanfani F, Moracci M. Ausili A, et al. Biochem J. 2004 Nov 15;384(Pt 1):69-78. doi: 10.1042/BJ20040646. Biochem J. 2004. PMID: 15283674 Free PMC article.

7

Recoding in archaea.

Cobucci-Ponzano B, Rossi M, Moracci M. Cobucci-Ponzano B, et al. Mol Microbiol. 2005 Jan;55(2):339-48. doi: 10.1111/j.1365-2958.2004.04400.x. Mol Microbiol. 2005. PMID: 15659155 Free article. Review.

8

Probing the catalytically essential residues of the alpha-L-fucosidase from the hyperthermophilic archaeon Sulfolobus solfataricus.

Cobucci-Ponzano B, Mazzone M, Rossi M, Moracci M. Cobucci-Ponzano B, et al. Biochemistry. 2005 Apr 26;44(16):6331-42. doi: 10.1021/bi047495f. Biochemistry. 2005. PMID: 15835922

9

Structural basis of the destabilization produced by an amino-terminal tag in the beta-glycosidase from the hyperthermophilic archeon Sulfolobus solfataricus.

Ausili A, Cobucci-Ponzano B, Di Lauro B, D'Avino R, Scirè A, Rossi M, Tanfani F, Moracci M. Ausili A, et al. Biochimie. 2006 Jul;88(7):807-17. doi: 10.1016/j.biochi.2006.01.009. Epub 2006 Feb 9. Biochimie. 2006. PMID: 16494988

10

The gene of an archaeal alpha-L-fucosidase is expressed by translational frameshifting.

Cobucci-Ponzano B, Conte F, Benelli D, Londei P, Flagiello A, Monti M, Pucci P, Rossi M, Moracci M. Cobucci-Ponzano B, et al. Nucleic Acids Res. 2006;34(15):4258-68. doi: 10.1093/nar/gkl574. Epub 2006 Aug 18. Nucleic Acids Res. 2006. PMID: 16920738 Free PMC article.

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