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Effects of spinal non-viral interleukin-10 gene therapy formulated with d-mannose in neuropathic interleukin-10 deficient mice: Behavioral characterization, mRNA and protein analysis in pain relevant tissues.
Vanderwall AG, Noor S, Sun MS, Sanchez JE, Yang XO, Jantzie LL, Mellios N, Milligan ED. Vanderwall AG, et al. Among authors: mellios n. Brain Behav Immun. 2018 Mar;69:91-112. doi: 10.1016/j.bbi.2017.11.004. Epub 2017 Nov 4. Brain Behav Immun. 2018. PMID: 29113923 Free PMC article.
LFA-1 antagonist (BIRT377) similarly reverses peripheral neuropathic pain in male and female mice with underlying sex divergent peripheral immune proinflammatory phenotypes.
Noor S, Sun MS, Vanderwall AG, Havard MA, Sanchez JE, Harris NW, Nysus MV, Norenberg JP, West HT, Wagner CR, Jantzie LL, Mellios N, Milligan ED. Noor S, et al. Among authors: mellios n. Neuroimmunol Neuroinflamm. 2019;6:10. doi: 10.20517/2347-8659.2019.18. Epub 2019 Jul 22. Neuroimmunol Neuroinflamm. 2019. PMID: 31763376 Free PMC article.
The LFA-1 antagonist BIRT377 reverses neuropathic pain in prenatal alcohol-exposed female rats via actions on peripheral and central neuroimmune function in discrete pain-relevant tissue regions.
Noor S, Sanchez JJ, Sun MS, Pervin Z, Sanchez JE, Havard MA, Epler LT, Nysus MV, Norenberg JP, Wagner CR, Davies S, Wagner JL, Savage DD, Jantzie LL, Mellios N, Milligan ED. Noor S, et al. Among authors: mellios n. Brain Behav Immun. 2020 Jul;87:339-358. doi: 10.1016/j.bbi.2020.01.002. Epub 2020 Jan 7. Brain Behav Immun. 2020. PMID: 31918004 Free PMC article.
Prenatal alcohol exposure dysregulates spinal and circulating immune cell circular RNA expression in adult female rats with chronic sciatic neuropathy.
Noor S, Pritha AN, Pasmay AA, Sanchez JE, Sanchez JJ, Fernandez-Oropeza AK, Sun MS, Dell'Orco M, Davies S, Savage DD, Mellios N, Milligan ED. Noor S, et al. Among authors: mellios n. Front Neurosci. 2023 Jun 9;17:1180308. doi: 10.3389/fnins.2023.1180308. eCollection 2023. Front Neurosci. 2023. PMID: 37360167 Free PMC article.
Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway.
Jiang S, Maphis NM, Binder J, Chisholm D, Weston L, Duran W, Peterson C, Zimmerman A, Mandell MA, Jett SD, Bigio E, Geula C, Mellios N, Weick JP, Rosenberg GA, Latz E, Heneka MT, Bhaskar K. Jiang S, et al. Among authors: mellios n. Cell Rep. 2021 Sep 21;36(12):109720. doi: 10.1016/j.celrep.2021.109720. Cell Rep. 2021. PMID: 34551296 Free PMC article.
36 results