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Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies.
Yang H, Kurtenbach S, Guo Y, Lohse I, Durante MA, Li J, Li Z, Al-Ali H, Li L, Chen Z, Field MG, Zhang P, Chen S, Yamamoto S, Li Z, Zhou Y, Nimer SD, Harbour JW, Wahlestedt C, Xu M, Yang FC. Yang H, et al. Among authors: li j, li z, li l. Blood. 2018 Jan 18;131(3):328-341. doi: 10.1182/blood-2017-06-789669. Epub 2017 Nov 7. Blood. 2018. PMID: 29113963 Free PMC article.
ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis.
Li Z, Zhang P, Yan A, Guo Z, Ban Y, Li J, Chen S, Yang H, He Y, Li J, Guo Y, Zhang W, Hajiramezanali E, An H, Fajardo D, Harbour JW, Ruan Y, Nimer SD, Yu P, Chen X, Xu M, Yang FC. Li Z, et al. Among authors: li j. Sci Adv. 2017 Jan 20;3(1):e1601602. doi: 10.1126/sciadv.1601602. eCollection 2017 Jan. Sci Adv. 2017. PMID: 28116354 Free PMC article.
Loss of Asxl2 leads to myeloid malignancies in mice.
Li J, He F, Zhang P, Chen S, Shi H, Sun Y, Guo Y, Yang H, Man N, Greenblatt S, Li Z, Guo Z, Zhou Y, Wang L, Morey L, Williams S, Chen X, Wang QT, Nimer SD, Yu P, Wang QF, Xu M, Yang FC. Li J, et al. Among authors: li z. Nat Commun. 2017 Jun 8;8:15456. doi: 10.1038/ncomms15456. Nat Commun. 2017. PMID: 28593990 Free PMC article.
DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks.
Venugopal K, Feng Y, Nowialis P, Xu H, Shabashvili DE, Berntsen CM, Kaur P, Krajcik KI, Taragjini C, Zaroogian Z, Casellas Román HL, Posada LM, Gunaratne C, Li J, Dupéré-Richer D, Bennett RL, Pondugula S, Riva A, Cogle CR, Opavsky R, Law BK, Bhaduri-McIntosh S, Kubicek S, Staber PB, Licht JD, Bird JE, Guryanova OA. Venugopal K, et al. Among authors: li j. Clin Cancer Res. 2022 Feb 15;28(4):756-769. doi: 10.1158/1078-0432.CCR-21-2863. Clin Cancer Res. 2022. PMID: 34716195 Free PMC article.
KDM6A regulates immune response genes in multiple myeloma.
Dupéré-Richer D, Riva A, Barwick BG, Maji S, Casellas Román H, Li J, De U, Sobh A, Quickstad G, Piper C, Kulis M, Ezponda T, Martín-Subero JI, Tonon G, Zhang W, Mitsiades CS, Boise LH, Bennett RL, Licht JD. Dupéré-Richer D, et al. Among authors: li j. Blood. 2024 Oct 3;144(14):1508-1520. doi: 10.1182/blood.2024024518. Blood. 2024. PMID: 39046770
MYB-activated models for testing therapeutic agents in adenoid cystic carcinoma.
Jiang Y, Gao R, Cao C, Forbes L, Li J, Freeberg S, Fredenburg KM, Justice JM, Silver NL, Wu L, Varma S, West R, Licht JD, Zajac-Kaye M, Kentsis A, Kaye FJ. Jiang Y, et al. Among authors: li j. Oral Oncol. 2019 Nov;98:147-155. doi: 10.1016/j.oraloncology.2019.09.005. Epub 2019 Oct 10. Oral Oncol. 2019. PMID: 31606723 Free PMC article.
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