Bian J - Search Results

1

Exploring the tetrahydroisoquinoline thiohydantoin scaffold blockade the androgen receptor as potent anti-prostate cancer agents.

Xu X, Ge R, Li L, Wang J, Lu X, Xue S, Chen X, Li Z, Bian J. Xu X, et al. Among authors: bian j. Eur J Med Chem. 2018 Jan 1;143:1325-1344. doi: 10.1016/j.ejmech.2017.10.031. Epub 2017 Oct 14. Eur J Med Chem. 2018. PMID: 29117897

2

2-Substituted 3-methylnaphtho[1,2-b]furan-4,5-diones as novel L-shaped ortho-quinone substrates for NAD(P)H:quinone oxidoreductase (NQO1).

Bian J, Deng B, Xu L, Xu X, Wang N, Hu T, Yao Z, Du J, Yang L, Lei Y, Li X, Sun H, Zhang X, You Q. Bian J, et al. Eur J Med Chem. 2014 Jul 23;82:56-67. doi: 10.1016/j.ejmech.2014.05.041. Epub 2014 May 14. Eur J Med Chem. 2014. PMID: 24874653

3

Synthesis and evaluation of (±)-dunnione and its ortho-quinone analogues as substrates for NAD(P)H:quinone oxidoreductase 1 (NQO1).

Bian J, Xu L, Deng B, Qian X, Fan J, Yang X, Liu F, Xu X, Guo X, Li X, Sun H, You Q, Zhang X. Bian J, et al. Bioorg Med Chem Lett. 2015 Mar 15;25(6):1244-8. doi: 10.1016/j.bmcl.2015.01.057. Epub 2015 Jan 31. Bioorg Med Chem Lett. 2015. PMID: 25677663

4

Novel natural-product-like caged xanthones with improved druglike properties and in vivo antitumor potency.

Wu Y, Hu M, Yang L, Li X, Bian J, Jiang F, Sun H, You Q, Zhang X. Wu Y, et al. Among authors: bian j. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2584-8. doi: 10.1016/j.bmcl.2015.04.031. Epub 2015 Apr 18. Bioorg Med Chem Lett. 2015. PMID: 25958244

5

Novel naphtho[2,1-d]oxazole-4,5-diones as NQO1 substrates with improved aqueous solubility: Design, synthesis, and in vivo antitumor evaluation.

Li X, Bian J, Wang N, Qian X, Gu J, Mu T, Fan J, Yang X, Li S, Yang T, Sun H, You Q, Zhang X. Li X, et al. Among authors: bian j. Bioorg Med Chem. 2016 Mar 1;24(5):1006-13. doi: 10.1016/j.bmc.2016.01.024. Epub 2016 Jan 16. Bioorg Med Chem. 2016. PMID: 26803578

6

Design and synthesis of indoline thiohydantoin derivatives based on enzalutamide as antiproliferative agents against prostate cancer.

Zuo M, Xu X, Xie Z, Ge R, Zhang Z, Li Z, Bian J. Zuo M, et al. Among authors: bian j. Eur J Med Chem. 2017 Jan 5;125:1002-1022. doi: 10.1016/j.ejmech.2016.10.049. Epub 2016 Oct 22. Eur J Med Chem. 2017. PMID: 27810589

7

Affinity-based small fluorescent probe for NAD(P)H:quinone oxidoreductase 1 (NQO1). Design, synthesis and pharmacological evaluation.

Bian J, Li X, Xu L, Wang N, Qian X, You Q, Zhang X. Bian J, et al. Eur J Med Chem. 2017 Feb 15;127:828-839. doi: 10.1016/j.ejmech.2016.10.062. Epub 2016 Nov 1. Eur J Med Chem. 2017. PMID: 27829520

8

Synthesis, evaluation and quantitative structure-activity relationship (QSAR) analysis of Wogonin derivatives as cytotoxic agents.

Bian J, Li T, Weng T, Wang J, Chen Y, Li Z. Bian J, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1012-1016. doi: 10.1016/j.bmcl.2016.12.076. Epub 2017 Jan 5. Bioorg Med Chem Lett. 2017. PMID: 28117202

9

Discovery of quinone-directed antitumor agents selectively bioactivated by NQO1 over CPR with improved safety profile.

Bian J, Li X, Wang N, Wu X, You Q, Zhang X. Bian J, et al. Eur J Med Chem. 2017 Mar 31;129:27-40. doi: 10.1016/j.ejmech.2017.02.004. Epub 2017 Feb 6. Eur J Med Chem. 2017. PMID: 28214631

10

2-Substituted 3,7,8-trimethylnaphtho[1,2-b]furan-4,5-diones as specific L-shaped NQO1-mediated redox modulators for the treatment of non-small cell lung cancer.

Zhang X, Bian J, Li X, Wu X, Dong Y, You Q. Zhang X, et al. Among authors: bian j. Eur J Med Chem. 2017 Sep 29;138:616-629. doi: 10.1016/j.ejmech.2017.06.028. Epub 2017 Jun 15. Eur J Med Chem. 2017. PMID: 28710963

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