Xu X - Search Results

1

Exploring the tetrahydroisoquinoline thiohydantoin scaffold blockade the androgen receptor as potent anti-prostate cancer agents.

Xu X, Ge R, Li L, Wang J, Lu X, Xue S, Chen X, Li Z, Bian J. Xu X, et al. Eur J Med Chem. 2018 Jan 1;143:1325-1344. doi: 10.1016/j.ejmech.2017.10.031. Epub 2017 Oct 14. Eur J Med Chem. 2018. PMID: 29117897

2

Design, synthesis and biological evaluation of 3-substituted indenoisoquinoline derivatives as topoisomerase I inhibitors.

Zhao Q, Xu X, Xie Z, Liu X, You Q, Guo Q, Zhong Y, Li Z. Zhao Q, et al. Among authors: xu x. Bioorg Med Chem Lett. 2016 Feb 1;26(3):1068-1072. doi: 10.1016/j.bmcl.2015.12.014. Epub 2015 Dec 7. Bioorg Med Chem Lett. 2016. PMID: 26725027

3

Progress in the mechanism and drug development of castration-resistant prostate cancer.

Zuo M, Xu X, Li T, Ge R, Li Z. Zuo M, et al. Among authors: xu x. Future Med Chem. 2016 May;8(7):765-88. doi: 10.4155/fmc.16.12. Epub 2016 May 5. Future Med Chem. 2016. PMID: 27149562 Review.

4

Design and synthesis of indoline thiohydantoin derivatives based on enzalutamide as antiproliferative agents against prostate cancer.

Zuo M, Xu X, Xie Z, Ge R, Zhang Z, Li Z, Bian J. Zuo M, et al. Among authors: xu x. Eur J Med Chem. 2017 Jan 5;125:1002-1022. doi: 10.1016/j.ejmech.2016.10.049. Epub 2016 Oct 22. Eur J Med Chem. 2017. PMID: 27810589

5

Discovery and synthesis of novel Wogonin derivatives with potent antitumor activity in vitro.

Wang J, Ge R, Qiu X, Xu X, Wei L, Li Z, Bian J. Wang J, et al. Among authors: xu x. Eur J Med Chem. 2017 Nov 10;140:421-434. doi: 10.1016/j.ejmech.2017.09.046. Epub 2017 Sep 22. Eur J Med Chem. 2017. PMID: 28987604

6

Degradation of Androgen Receptor through Small Molecules for Prostate Cancer.

Ge R, Xu X, Xu P, Li L, Li Z, Bian J. Ge R, et al. Among authors: xu p, xu x. Curr Cancer Drug Targets. 2018;18(7):652-667. doi: 10.2174/1568009617666171107103936. Curr Cancer Drug Targets. 2018. PMID: 29110617 Review.

7

Palladium(II)-Catalyzed Reaction of Lawsones and Propargyl Carbonates: Construction of 2,3-Furanonaphthoquinones and Evaluation as Potential Indoleamine 2,3-Dioxygenase Inhibitors.

Feng X, Qiu X, Huang H, Wang J, Xu X, Xu P, Ge R, Liu X, Li Z, Bian J. Feng X, et al. Among authors: xu p, xu x. J Org Chem. 2018 Aug 3;83(15):8003-8010. doi: 10.1021/acs.joc.8b00872. Epub 2018 Jun 15. J Org Chem. 2018. PMID: 29882670

8

Overview of the Development of Glutaminase Inhibitors: Achievements and Future Directions.

Xu X, Meng Y, Li L, Xu P, Wang J, Li Z, Bian J. Xu X, et al. Among authors: xu p. J Med Chem. 2019 Feb 14;62(3):1096-1115. doi: 10.1021/acs.jmedchem.8b00961. Epub 2018 Sep 7. J Med Chem. 2019. PMID: 30148361

9

Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity.

Bian J, Ren J, Li Y, Wang J, Xu X, Feng Y, Tang H, Wang Y, Li Z. Bian J, et al. Among authors: xu x. Bioorg Chem. 2018 Dec;81:373-381. doi: 10.1016/j.bioorg.2018.08.028. Epub 2018 Aug 30. Bioorg Chem. 2018. PMID: 30196207

10

Discovery and development of small molecule modulators targeting glutamine metabolism.

Li L, Meng Y, Li Z, Dai W, Xu X, Bi X, Bian J. Li L, et al. Among authors: xu x. Eur J Med Chem. 2019 Feb 1;163:215-242. doi: 10.1016/j.ejmech.2018.11.066. Epub 2018 Nov 28. Eur J Med Chem. 2019. PMID: 30522056 Review.

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