Hu LH - Search Results

1

Tumor-targeting efficacy of a BF211 prodrug through hydrolysis by fibroblast activation protein-α.

Chai XP, Sun GL, Fang YF, Hu LH, Liu X, Zhang XW. Chai XP, et al. Among authors: hu lh. Acta Pharmacol Sin. 2018 Mar;39(3):415-424. doi: 10.1038/aps.2017.121. Epub 2017 Nov 9. Acta Pharmacol Sin. 2018. PMID: 29119969 Free PMC article.

2

Bufalin derivative BF211 inhibits proteasome activity in human lung cancer cells in vitro by inhibiting β1 subunit expression and disrupting proteasome assembly.

Sun P, Feng LX, Zhang DM, Liu M, Liu W, Mi T, Wu WY, Jiang BH, Yang M, Hu LH, Guo DA, Liu X. Sun P, et al. Among authors: hu lh. Acta Pharmacol Sin. 2016 Jul;37(7):908-18. doi: 10.1038/aps.2016.30. Epub 2016 May 30. Acta Pharmacol Sin. 2016. PMID: 27238210 Free PMC article.

3

Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid β production and clearance.

Guo XD, Sun GL, Zhou TT, Xu X, Zhu ZY, Rukachaisirikul V, Hu LH, Shen X. Guo XD, et al. Among authors: hu lh. Acta Pharmacol Sin. 2016 Sep;37(10):1281-1297. doi: 10.1038/aps.2016.80. Epub 2016 Aug 29. Acta Pharmacol Sin. 2016. PMID: 27569389 Free PMC article.

4

LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy.

Guo XD, Sun GL, Zhou TT, Wang YY, Xu X, Shi XF, Zhu ZY, Rukachaisirikul V, Hu LH, Shen X. Guo XD, et al. Among authors: hu lh. Acta Pharmacol Sin. 2017 Aug;38(8):1104-1119. doi: 10.1038/aps.2016.128. Epub 2017 Jun 26. Acta Pharmacol Sin. 2017. PMID: 28649128 Free PMC article.

5

Synthesis and cytotoxicity evaluation of 4'-amino-4'-dehydroxyloleandrin derivatives.

Chen H, Lei M, Ma B, Liu M, Guo D, Liu X, Hu L. Chen H, et al. Fitoterapia. 2016 Sep;113:85-90. doi: 10.1016/j.fitote.2016.07.002. Epub 2016 Jul 16. Fitoterapia. 2016. PMID: 27431773

6

Design, synthesis and biological evaluation of LX2343 derivatives as neuroprotective agents for the treatment of Alzheimer's disease.

Sun G, Wang J, Guo X, Lei M, Zhang Y, Wang X, Shen X, Hu L. Sun G, et al. Eur J Med Chem. 2018 Feb 10;145:622-633. doi: 10.1016/j.ejmech.2017.12.080. Epub 2018 Jan 2. Eur J Med Chem. 2018. PMID: 29339255

7

A Novel Bufalin Derivative Exhibited Stronger Apoptosis-Inducing Effect than Bufalin in A549 Lung Cancer Cells and Lower Acute Toxicity in Mice.

Liu M, Feng LX, Sun P, Liu W, Wu WY, Jiang BH, Yang M, Hu LH, Guo DA, Liu X. Liu M, et al. Among authors: hu lh. PLoS One. 2016 Jul 26;11(7):e0159789. doi: 10.1371/journal.pone.0159789. eCollection 2016. PLoS One. 2016. PMID: 27459387 Free PMC article.

8

Palladium-Catalyzed Formylation of Aryl Iodides with HCOOH as CO Source.

Sun G, Lv X, Zhang Y, Lei M, Hu L. Sun G, et al. Org Lett. 2017 Aug 18;19(16):4235-4238. doi: 10.1021/acs.orglett.7b01882. Epub 2017 Aug 7. Org Lett. 2017. PMID: 28782963

9

Cytotoxic cardenolides from the root bark of Calotropis gigantea.

You H, Lei M, Song W, Chen H, Meng Y, Guo D, Liu X, Hu L. You H, et al. Steroids. 2013 Oct;78(10):1029-34. doi: 10.1016/j.steroids.2013.06.002. Epub 2013 Jul 12. Steroids. 2013. PMID: 23851141

10

Synthesis and biological evaluation of bufalin-3-yl nitrogen-containing-carbamate derivatives as anticancer agents.

Lei M, Xiao Z, Ma B, Chen Y, Liu M, Liu J, Guo D, Liu X, Hu L. Lei M, et al. Steroids. 2016 Apr;108:56-60. doi: 10.1016/j.steroids.2016.01.011. Epub 2016 Jan 28. Steroids. 2016. PMID: 26827628

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