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Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells.
Chandrasekaran A, Avci HX, Ochalek A, Rösingh LN, Molnár K, László L, Bellák T, Téglási A, Pesti K, Mike A, Phanthong P, Bíró O, Hall V, Kitiyanant N, Krause KH, Kobolák J, Dinnyés A. Chandrasekaran A, et al. Among authors: ochalek a. Stem Cell Res. 2017 Dec;25:139-151. doi: 10.1016/j.scr.2017.10.010. Epub 2017 Oct 14. Stem Cell Res. 2017. PMID: 29128818 Free article.
Neurosphere Based Differentiation of Human iPSC Improves Astrocyte Differentiation.
Zhou S, Szczesna K, Ochalek A, Kobolák J, Varga E, Nemes C, Chandrasekaran A, Rasmussen M, Cirera S, Hyttel P, Dinnyés A, Freude KK, Avci HX. Zhou S, et al. Among authors: ochalek a. Stem Cells Int. 2016;2016:4937689. doi: 10.1155/2016/4937689. Epub 2015 Dec 21. Stem Cells Int. 2016. PMID: 26798357 Free PMC article.
The positional identity of iPSC-derived neural progenitor cells along the anterior-posterior axis is controlled in a dosage-dependent manner by bFGF and EGF.
Zhou S, Ochalek A, Szczesna K, Avci HX, Kobolák J, Varga E, Rasmussen M, Holst B, Cirera S, Hyttel P, Freude KK, Dinnyés A. Zhou S, et al. Among authors: ochalek a. Differentiation. 2016 Oct-Nov;92(4):183-194. doi: 10.1016/j.diff.2016.06.002. Epub 2016 Jun 16. Differentiation. 2016. PMID: 27321088
Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.
Ochalek A, Mihalik B, Avci HX, Chandrasekaran A, Téglási A, Bock I, Giudice ML, Táncos Z, Molnár K, László L, Nielsen JE, Holst B, Freude K, Hyttel P, Kobolák J, Dinnyés A. Ochalek A, et al. Alzheimers Res Ther. 2017 Dec 1;9(1):90. doi: 10.1186/s13195-017-0317-z. Alzheimers Res Ther. 2017. PMID: 29191219 Free PMC article.