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Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis.
Bakkar N, Kovalik T, Lorenzini I, Spangler S, Lacoste A, Sponaugle K, Ferrante P, Argentinis E, Sattler R, Bowser R. Bakkar N, et al. Among authors: spangler s. Acta Neuropathol. 2018 Feb;135(2):227-247. doi: 10.1007/s00401-017-1785-8. Epub 2017 Nov 13. Acta Neuropathol. 2018. PMID: 29134320 Free PMC article.
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans.
Chen KS, Menezes K, Rodgers JB, O'Hara DM, Tran N, Fujisawa K, Ishikura S, Khodaei S, Chau H, Cranston A, Kapadia M, Pawar G, Ping S, Krizus A, Lacoste A, Spangler S, Visanji NP, Marras C, Majbour NK, El-Agnaf OMA, Lozano AM, Culotti J, Suo S, Ryu WS, Kalia SK, Kalia LV. Chen KS, et al. Among authors: spangler s. Mol Neurodegener. 2021 Nov 12;16(1):77. doi: 10.1186/s13024-021-00497-6. Mol Neurodegener. 2021. PMID: 34772429 Free PMC article.
Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2.
Choi BK, Dayaram T, Parikh N, Wilkins AD, Nagarajan M, Novikov IB, Bachman BJ, Jung SY, Haas PJ, Labrie JL, Pickering CR, Adikesavan AK, Regenbogen S, Kato L, Lelescu A, Buchovecky CM, Zhang H, Bao SH, Boyer S, Weber G, Scott KL, Chen Y, Spangler S, Donehower LA, Lichtarge O. Choi BK, et al. Among authors: spangler s. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10666-10671. doi: 10.1073/pnas.1806643115. Epub 2018 Sep 28. Proc Natl Acad Sci U S A. 2018. PMID: 30266789 Free PMC article.
Exposome-Scale Investigations Guided by Global Metabolomics, Pathway Analysis, and Cognitive Computing.
Warth B, Spangler S, Fang M, Johnson CH, Forsberg EM, Granados A, Martin RL, Domingo-Almenara X, Huan T, Rinehart D, Montenegro-Burke JR, Hilmers B, Aisporna A, Hoang LT, Uritboonthai W, Benton HP, Richardson SD, Williams AJ, Siuzdak G. Warth B, et al. Among authors: spangler s. Anal Chem. 2017 Nov 7;89(21):11505-11513. doi: 10.1021/acs.analchem.7b02759. Epub 2017 Oct 9. Anal Chem. 2017. PMID: 28945073
Persistent plasma waves in interstellar space detected by Voyager 1.
Koch Ocker S, Cordes JM, Chatterjee S, Gurnett DA, Kurth WS, Spangler SR. Koch Ocker S, et al. Among authors: spangler sr. Nat Astron. 2021 Aug;5:761-765. doi: 10.1038/s41550-021-01363-7. Epub 2021 May 10. Nat Astron. 2021. PMID: 35005245 Free PMC article.
112 results