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Force generation by the growth of amyloid aggregates.
Herling TW, Garcia GA, Michaels TC, Grentz W, Dean J, Shimanovich U, Gang H, Müller T, Kav B, Terentjev EM, Dobson CM, Knowles TP. Herling TW, et al. Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9524-9. doi: 10.1073/pnas.1417326112. Epub 2015 Jul 20. Proc Natl Acad Sci U S A. 2015. PMID: 26195762 Free PMC article.
Fluctuations in the Kinetics of Linear Protein Self-Assembly.
Michaels TC, Dear AJ, Kirkegaard JB, Saar KL, Weitz DA, Knowles TP. Michaels TC, et al. Phys Rev Lett. 2016 Jun 24;116(25):258103. doi: 10.1103/PhysRevLett.116.258103. Epub 2016 Jun 21. Phys Rev Lett. 2016. PMID: 27391756
Dynamic microfluidic control of supramolecular peptide self-assembly.
Arnon ZA, Vitalis A, Levin A, Michaels TCT, Caflisch A, Knowles TPJ, Adler-Abramovich L, Gazit E. Arnon ZA, et al. Among authors: knowles tpj. Nat Commun. 2016 Oct 25;7:13190. doi: 10.1038/ncomms13190. Nat Commun. 2016. PMID: 27779182 Free PMC article.
Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species.
Iljina M, Hong L, Horrocks MH, Ludtmann MH, Choi ML, Hughes CD, Ruggeri FS, Guilliams T, Buell AK, Lee JE, Gandhi S, Lee SF, Bryant CE, Vendruscolo M, Knowles TPJ, Dobson CM, De Genst E, Klenerman D. Iljina M, et al. Among authors: knowles tpj. BMC Biol. 2017 Jul 3;15(1):57. doi: 10.1186/s12915-017-0390-6. BMC Biol. 2017. PMID: 28673288 Free PMC article.
414 results