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Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro-Fibrotic Signaling.
Haller ST, Yan Y, Drummond CA, Xie J, Tian J, Kennedy DJ, Shilova VY, Xie Z, Liu J, Cooper CJ, Malhotra D, Shapiro JI, Fedorova OV, Bagrov AY. Haller ST, et al. Among authors: shapiro ji. J Am Heart Assoc. 2016 Sep 30;5(10):e004106. doi: 10.1161/JAHA.116.004106. J Am Heart Assoc. 2016. PMID: 27694325 Free PMC article.
Attenuation of Na/K-ATPase Mediated Oxidant Amplification with pNaKtide Ameliorates Experimental Uremic Cardiomyopathy.
Liu J, Tian J, Chaudhry M, Maxwell K, Yan Y, Wang X, Shah PT, Khawaja AA, Martin R, Robinette TJ, El-Hamdani A, Dodrill MW, Sodhi K, Drummond CA, Haller ST, Kennedy DJ, Abraham NG, Xie Z, Shapiro JI. Liu J, et al. Among authors: shapiro ji. Sci Rep. 2016 Oct 4;6:34592. doi: 10.1038/srep34592. Sci Rep. 2016. PMID: 27698370 Free PMC article.
Central Role for Adipocyte Na,K-ATPase Oxidant Amplification Loop in the Pathogenesis of Experimental Uremic Cardiomyopathy.
Sodhi K, Wang X, Chaudhry MA, Lakhani HV, Zehra M, Pratt R, Nawab A, Cottrill CL, Snoad B, Bai F, Denvir J, Liu J, Sanabria JR, Xie Z, Abraham NG, Shapiro JI. Sodhi K, et al. Among authors: shapiro ji. J Am Soc Nephrol. 2020 Aug;31(8):1746-1760. doi: 10.1681/ASN.2019101070. Epub 2020 Jun 25. J Am Soc Nephrol. 2020. Retraction in: J Am Soc Nephrol. 2023 Mar 1;34(3):517-518. doi: 10.1681/ASN.0000000000000051 PMID: 32587074 Free PMC article. Retracted.
Blockage of the Na-K-ATPase signaling-mediated oxidant amplification loop elongates red blood cell half-life and ameliorates uremic anemia induced by 5/6th PNx in C57BL/6 mice.
Liu J, Chaudhry M, Bai F, Chuang J, Chaudhry H, Al-Astal AY, Nie Y, Sollars V, Sodhi K, Seligman P, Shapiro JI. Liu J, et al. Among authors: shapiro ji. Am J Physiol Renal Physiol. 2022 Jun 1;322(6):F655-F666. doi: 10.1152/ajprenal.00189.2021. Epub 2022 Apr 18. Am J Physiol Renal Physiol. 2022. PMID: 35435001 Free PMC article.
269 results