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963 results

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Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model.
Kawaguchi K, Igarashi K, Li S, Han Q, Tan Y, Kiyuna T, Miyake K, Murakami T, Chmielowski B, Nelson SD, Russell TA, Dry SM, Li Y, Unno M, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: unno m. Oncotarget. 2017 Aug 12;8(49):85516-85525. doi: 10.18632/oncotarget.20231. eCollection 2017 Oct 17. Oncotarget. 2017. PMID: 29156737 Free PMC article.
Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model.
Kawaguchi K, Murakami T, Chmielowski B, Igarashi K, Kiyuna T, Unno M, Nelson SD, Russell TA, Dry SM, Li Y, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: unno m. Oncotarget. 2016 Nov 1;7(44):71737-71743. doi: 10.18632/oncotarget.12328. Oncotarget. 2016. PMID: 27690220 Free PMC article.
Tumor-targeting Salmonella typhimurium A1-R combined with temozolomide regresses malignant melanoma with a BRAF-V600E mutation in a patient-derived orthotopic xenograft (PDOX) model.
Kawaguchi K, Igarashi K, Murakami T, Chmielowski B, Kiyuna T, Zhao M, Zhang Y, Singh A, Unno M, Nelson SD, Russell TA, Dry SM, Li Y, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: unno m. Oncotarget. 2016 Dec 27;7(52):85929-85936. doi: 10.18632/oncotarget.13231. Oncotarget. 2016. PMID: 27835903 Free PMC article.
Tumor-Targeting Salmonella typhimurium A1-R Sensitizes Melanoma With a BRAF-V600E Mutation to Vemurafenib in a Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model.
Kawaguchi K, Igarashi K, Murakami T, Zhao M, Zhang Y, Chmielowski B, Kiyuna T, Nelson SD, Russell TA, Dry SM, Li Y, Unno M, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: unno m. J Cell Biochem. 2017 Aug;118(8):2314-2319. doi: 10.1002/jcb.25886. Epub 2017 Apr 25. J Cell Biochem. 2017. PMID: 28106277
MK2461, a Multitargeted Kinase Inhibitor, Suppresses the Progression of Pancreatic Cancer by Disrupting the Interaction Between Pancreatic Cancer Cells and Stellate Cells.
Inoue K, Ohtsuka H, Tachikawa M, Motoi F, Shijo M, Douchi D, Kawasaki S, Kawaguchi K, Masuda K, Fukase K, Naitoh T, Katayose Y, Egawa S, Unno M, Terasaki T. Inoue K, et al. Among authors: unno m. Pancreas. 2017 Apr;46(4):557-566. doi: 10.1097/MPA.0000000000000778. Pancreas. 2017. PMID: 28196027
Combination of gemcitabine and docetaxel regresses both gastric leiomyosarcoma proliferation and invasion in an imageable patient-derived orthotopic xenograft (iPDOX) model.
Kawaguchi K, Igarashi K, Murakami T, Kiyuna T, Nelson SD, Dry SM, Li Y, Russell TA, Singh AS, Chmielowski B, Unno M, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: unno m. Cell Cycle. 2017 Jun 3;16(11):1063-1069. doi: 10.1080/15384101.2017.1314406. Epub 2017 Apr 20. Cell Cycle. 2017. PMID: 28426279 Free PMC article.
963 results