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Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies.
Prabhu VV, Talekar MK, Lulla AR, Kline CLB, Zhou L, Hall J, Van den Heuvel APJ, Dicker DT, Babar J, Grupp SA, Garnett MJ, McDermott U, Benes CH, Pu JJ, Claxton DF, Khan N, Oster W, Allen JE, El-Deiry WS. Prabhu VV, et al. Among authors: dicker dt. Cell Cycle. 2018;17(4):468-478. doi: 10.1080/15384101.2017.1403689. Epub 2018 Feb 19. Cell Cycle. 2018. PMID: 29157092 Free PMC article.
Repression of BRCA1 through a feedback loop involving p53.
MacLachlan TK, Dash BC, Dicker DT, El-Deiry WS. MacLachlan TK, et al. Among authors: dicker dt. J Biol Chem. 2000 Oct 13;275(41):31869-75. doi: 10.1074/jbc.M003338200. J Biol Chem. 2000. PMID: 10884389 Free article.
107 results