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A synthetic chalcone derivative, 2-hydroxy-3',5,5'-trimethoxychalcone (DK-139), suppresses the TNFα-induced invasive capability of MDA-MB-231 human breast cancer cells by inhibiting NF-κB-mediated GROα expression.
Lee DY, Lee DH, Jung JY, Koh D, Kim GS, Ahn YS, Lee YH, Lim Y, Shin SY. Lee DY, et al. Among authors: lee dh, lee yh. Bioorg Med Chem Lett. 2016 Jan 1;26(1):203-8. doi: 10.1016/j.bmcl.2015.10.094. Epub 2015 Oct 30. Bioorg Med Chem Lett. 2016. PMID: 26602275
8,042 results