Hughes JH - Search Results

1

Hughes JH, Scheibel KE, Bremer AW. Hughes JH, et al. Nature. 2017 Nov 23;551(7681):440. doi: 10.1038/d41586-017-07234-4. Nature. 2017. PMID: 29168839 No abstract available.

2

[No title available]

[No authors listed] [No authors listed] PMID: 32080595

3

Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium.

Turco MY, Gardner L, Hughes J, Cindrova-Davies T, Gomez MJ, Farrell L, Hollinshead M, Marsh SGE, Brosens JJ, Critchley HO, Simons BD, Hemberger M, Koo BK, Moffett A, Burton GJ. Turco MY, et al. Nat Cell Biol. 2017 May;19(5):568-577. doi: 10.1038/ncb3516. Epub 2017 Apr 10. Nat Cell Biol. 2017. PMID: 28394884 Free PMC article.

4

Comparing two-sample log-linear exposure estimation with Bayesian model-informed precision dosing of tobramycin in adult patients with cystic fibrosis.

Tong DMH, Hughes M-SA, Hu J, Pearson JC, Kubiak DW, Dionne BW, Hughes JH. Tong DMH, et al. Among authors: hughes jh. Antimicrob Agents Chemother. 2025 Jan 10:e0104024. doi: 10.1128/aac.01040-24. Online ahead of print. Antimicrob Agents Chemother. 2025. PMID: 39791873

5

An anatomical investigation of alkaptonuria: Novel insights into ochronosis of cartilage and bone.

Hughes JH, Charlesworth G, Prior A, Tierney CM, Rothwell PD, Thomas NP, Ranganath LR, Gallagher JA, Bond AP. Hughes JH, et al. J Anat. 2024 Dec 20. doi: 10.1111/joa.14190. Online ahead of print. J Anat. 2024. PMID: 39707148

6

Exposure-response modeling of liver fat imaging endpoints in non-alcoholic fatty liver disease populations administered ervogastat alone and co-administered with clesacostat.

Hughes JH, Amin NB, Wojciechowski J, Vourvahis M. Hughes JH, et al. CPT Pharmacometrics Syst Pharmacol. 2024 Nov 20. doi: 10.1002/psp4.13275. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 39564924 Free article.

7

Population pharmacokinetic modeling of zavegepant, a calcitonin gene-related peptide receptor antagonist, in healthy adults and patients with migraine.

Comisar CM, Francis J, Hughes JH, Bhardwaj R, Bertz R, Liu J. Comisar CM, et al. Among authors: hughes jh. CPT Pharmacometrics Syst Pharmacol. 2025 Jan;14(1):179-191. doi: 10.1002/psp4.13257. Epub 2024 Nov 3. CPT Pharmacometrics Syst Pharmacol. 2025. PMID: 39492601 Free PMC article. Clinical Trial.

8

Impacts of age and BMI on vancomycin model choice in a Bayesian software: Lessons from a very large multi-site retrospective study.

Hughes MA, Lee T, Faldasz JD, Hughes JH. Hughes MA, et al. Among authors: hughes jh. Pharmacotherapy. 2024 Oct;44(10):794-802. doi: 10.1002/phar.4613. Epub 2024 Oct 9. Pharmacotherapy. 2024. PMID: 39382218

9

Joint replacement risk is markedly increased in alkaptonuria (AKU) in those with prior arthroplasty.

Ranganath LR, Khedr M, Norman BP, Hughes JH, Imrich R, Arnoux JB, Olsson B, Rudebeck M, Gallagher JA, Bou-Gharios G. Ranganath LR, et al. Among authors: hughes jh. Mol Genet Metab Rep. 2024 May 24;40:101097. doi: 10.1016/j.ymgmr.2024.101097. eCollection 2024 Sep. Mol Genet Metab Rep. 2024. PMID: 38846518 Free PMC article.

10

Concentration-QTc and cardiac safety analysis of single and multiple zavegepant nasal spray doses in healthy participants to support approval.

Hughes JH, Bertz R, Bhardwaj R, Donohue MK, Madonia J, Anderson MS, Morris BA, Croop RS, Liu J. Hughes JH, et al. CPT Pharmacometrics Syst Pharmacol. 2024 Jun;13(6):1044-1054. doi: 10.1002/psp4.13140. Epub 2024 May 29. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38812357 Free PMC article. Clinical Trial.

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