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Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically.
Putoczki TL, Thiem S, Loving A, Busuttil RA, Wilson NJ, Ziegler PK, Nguyen PM, Preaudet A, Farid R, Edwards KM, Boglev Y, Luwor RB, Jarnicki A, Horst D, Boussioutas A, Heath JK, Sieber OM, Pleines I, Kile BT, Nash A, Greten FR, McKenzie BS, Ernst M. Putoczki TL, et al. Cancer Cell. 2013 Aug 12;24(2):257-71. doi: 10.1016/j.ccr.2013.06.017. Cancer Cell. 2013. PMID: 23948300 Free article.
Complementarity and redundancy of IL-22-producing innate lymphoid cells.
Rankin LC, Girard-Madoux MJ, Seillet C, Mielke LA, Kerdiles Y, Fenis A, Wieduwild E, Putoczki T, Mondot S, Lantz O, Demon D, Papenfuss AT, Smyth GK, Lamkanfi M, Carotta S, Renauld JC, Shi W, Carpentier S, Soos T, Arendt C, Ugolini S, Huntington ND, Belz GT, Vivier E. Rankin LC, et al. Among authors: putoczki t. Nat Immunol. 2016 Feb;17(2):179-86. doi: 10.1038/ni.3332. Epub 2015 Nov 30. Nat Immunol. 2016. PMID: 26595889 Free PMC article.
Th17 cell differentiation proceeds independently of IRF8.
Newman DM, Leung PS, Putoczki TL, Nutt SL, Cretney E. Newman DM, et al. Immunol Cell Biol. 2016 Sep;94(8):796-801. doi: 10.1038/icb.2016.33. Epub 2016 May 3. Immunol Cell Biol. 2016. PMID: 27140932
87 results