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Pharmacokinetic-Pharmacodynamic Target Attainment Analyses To Support Dose Selection for ME1100, an Arbekacin Inhalation Solution.
Bhavnani SM, Hammel JP, Lakota EA, Safir MC, VanScoy BD, Nagira Y, Rubino CM, Sato N, Koresawa T, Kondo K, Ambrose PG. Bhavnani SM, et al. Among authors: safir mc. Antimicrob Agents Chemother. 2020 Sep 21;64(10):e02367-19. doi: 10.1128/AAC.02367-19. Print 2020 Sep 21. Antimicrob Agents Chemother. 2020. PMID: 32661000 Free PMC article.
Population Pharmacokinetic Analyses for Omadacycline Using Phase 1 and 3 Data.
Lakota EA, Van Wart SA, Trang M, Tzanis E, Bhavnani SM, Safir MC, Friedrich L, Steenbergen JN, Ambrose PG, Rubino CM. Lakota EA, et al. Among authors: safir mc. Antimicrob Agents Chemother. 2020 Jun 23;64(7):e02263-19. doi: 10.1128/AAC.02263-19. Print 2020 Jun 23. Antimicrob Agents Chemother. 2020. PMID: 32340986 Free PMC article.
A Phase 1 First-in-Human Single-Ascending-Dose Trial With ESB1609, a Selective Agonist to the Sphingosine-1-Phosphate Receptor 5.
France NP, Rubino C, Safir MC, Maurer M, Duong T, Singamsetty D, Abd-Elaziz K, Chou T, Sankaranarayanan S, Ettema M, Cosford R, Dogterom P, Liu E, Barlow C. France NP, et al. Among authors: safir mc. Clin Pharmacol Drug Dev. 2023 Jun;12(6):625-638. doi: 10.1002/cpdd.1256. Epub 2023 May 16. Clin Pharmacol Drug Dev. 2023. PMID: 37191222 Clinical Trial.
Evaluation of the Impact of Comorbidities on Omadacycline Pharmacokinetics.
Trang M, Lakota EA, Safir MC, Bhavnani SM, Friedrich L, Steenbergen JN, McGovern PC, Tzanis E, Rubino CM. Trang M, et al. Among authors: safir mc. Antimicrob Agents Chemother. 2023 Apr 18;67(4):e0239721. doi: 10.1128/aac.02397-21. Epub 2023 Mar 14. Antimicrob Agents Chemother. 2023. PMID: 36916956 Free PMC article.
Omadacycline Pharmacokinetics: Influence of Mortality Risk Score among Patients with Community-Acquired Bacterial Pneumonia.
Trang M, Hammel JP, Lakota EA, Safir MC, Bhavnani SM, Friedrich L, Steenbergen JN, McGovern PC, Tzanis E, Rubino CM. Trang M, et al. Among authors: safir mc. Antimicrob Agents Chemother. 2023 Jan 24;67(1):e0220121. doi: 10.1128/aac.02201-21. Epub 2022 Dec 19. Antimicrob Agents Chemother. 2023. PMID: 36533934 Free PMC article. No abstract available.