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Page 1
Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma.
Gonzalez-Meljem JM, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Mousavy-Gharavy SN, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Martinez-Barbera JP. Gonzalez-Meljem JM, et al. Among authors: goding cr. Nat Commun. 2017 Nov 28;8(1):1819. doi: 10.1038/s41467-017-01992-5. Nat Commun. 2017. PMID: 29180744 Free PMC article.
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.
Müller J, Krijgsman O, Tsoi J, Robert L, Hugo W, Song C, Kong X, Possik PA, Cornelissen-Steijger PD, Geukes Foppen MH, Kemper K, Goding CR, McDermott U, Blank C, Haanen J, Graeber TG, Ribas A, Lo RS, Peeper DS. Müller J, et al. Among authors: goding cr. Nat Commun. 2014 Dec 15;5:5712. doi: 10.1038/ncomms6712. Nat Commun. 2014. PMID: 25502142 Free PMC article.
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target.
Apps JR, Carreno G, Gonzalez-Meljem JM, Haston S, Guiho R, Cooper JE, Manshaei S, Jani N, Hölsken A, Pettorini B, Beynon RJ, Simpson DM, Fraser HC, Hong Y, Hallang S, Stone TJ, Virasami A, Donson AM, Jones D, Aquilina K, Spoudeas H, Joshi AR, Grundy R, Storer LCD, Korbonits M, Hilton DA, Tossell K, Thavaraj S, Ungless MA, Gil J, Buslei R, Hankinson T, Hargrave D, Goding C, Andoniadou CL, Brogan P, Jacques TS, Williams HJ, Martinez-Barbera JP. Apps JR, et al. Acta Neuropathol. 2018 May;135(5):757-777. doi: 10.1007/s00401-018-1830-2. Epub 2018 Mar 14. Acta Neuropathol. 2018. PMID: 29541918 Free PMC article.
Cancer: pathological nuclear reprogramming?
Goding CR, Pei D, Lu X. Goding CR, et al. Nat Rev Cancer. 2014 Aug;14(8):568-73. doi: 10.1038/nrc3781. Epub 2014 Jul 17. Nat Rev Cancer. 2014. PMID: 25030952 Review.
MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment.
Riesenberg S, Groetchen A, Siddaway R, Bald T, Reinhardt J, Smorra D, Kohlmeyer J, Renn M, Phung B, Aymans P, Schmidt T, Hornung V, Davidson I, Goding CR, Jönsson G, Landsberg J, Tüting T, Hölzel M. Riesenberg S, et al. Among authors: goding cr. Nat Commun. 2015 Nov 4;6:8755. doi: 10.1038/ncomms9755. Nat Commun. 2015. PMID: 26530832 Free PMC article.
Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers.
Pérez-Guijarro E, Karras P, Cifdaloz M, Martínez-Herranz R, Cañón E, Graña O, Horcajada-Reales C, Alonso-Curbelo D, Calvo TG, Gómez-López G, Bellora N, Riveiro-Falkenbach E, Ortiz-Romero PL, Rodríguez-Peralto JL, Maestre L, Roncador G, de Agustín Asensio JC, Goding CR, Eyras E, Megías D, Méndez R, Soengas MS. Pérez-Guijarro E, et al. Among authors: goding cr. Nat Commun. 2016 Nov 18;7:13418. doi: 10.1038/ncomms13418. Nat Commun. 2016. PMID: 27857118 Free PMC article.
Palmitoylation-dependent activation of MC1R prevents melanomagenesis.
Chen S, Zhu B, Yin C, Liu W, Han C, Chen B, Liu T, Li X, Chen X, Li C, Hu L, Zhou J, Xu ZX, Gao X, Wu X, Goding CR, Cui R. Chen S, et al. Among authors: goding cr. Nature. 2017 Sep 21;549(7672):399-403. doi: 10.1038/nature23887. Epub 2017 Sep 6. Nature. 2017. PMID: 28869973 Free PMC article.
Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads.
Chen S, Han C, Miao X, Li X, Yin C, Zou J, Liu M, Li S, Stawski L, Zhu B, Shi Q, Xu ZX, Li C, Goding CR, Zhou J, Cui R. Chen S, et al. Among authors: goding cr. Nat Commun. 2019 Feb 20;10(1):877. doi: 10.1038/s41467-019-08691-3. Nat Commun. 2019. PMID: 30787281 Free PMC article.
192 results