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Restoration of high-sensitivity and adapting vision with a cone opsin.
Berry MH, Holt A, Salari A, Veit J, Visel M, Levitz J, Aghi K, Gaub BM, Sivyer B, Flannery JG, Isacoff EY. Berry MH, et al. Among authors: holt a. Nat Commun. 2019 Mar 15;10(1):1221. doi: 10.1038/s41467-019-09124-x. Nat Commun. 2019. PMID: 30874546 Free PMC article.
Photopharmacology for vision restoration.
Berry MH, Holt A, Broichhagen J, Donthamsetti P, Flannery JG, Isacoff EY. Berry MH, et al. Among authors: holt a. Curr Opin Pharmacol. 2022 Aug;65:102259. doi: 10.1016/j.coph.2022.102259. Epub 2022 Jun 21. Curr Opin Pharmacol. 2022. PMID: 35749908 Free article. Review.
Restoration of visual function by expression of a light-gated mammalian ion channel in retinal ganglion cells or ON-bipolar cells.
Gaub BM, Berry MH, Holt AE, Reiner A, Kienzler MA, Dolgova N, Nikonov S, Aguirre GD, Beltran WA, Flannery JG, Isacoff EY. Gaub BM, et al. Among authors: holt ae. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):E5574-83. doi: 10.1073/pnas.1414162111. Epub 2014 Dec 8. Proc Natl Acad Sci U S A. 2014. PMID: 25489083 Free PMC article.
ChIP-seq accurately predicts tissue-specific activity of enhancers.
Visel A, Blow MJ, Li Z, Zhang T, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Wright C, Chen F, Afzal V, Ren B, Rubin EM, Pennacchio LA. Visel A, et al. Among authors: holt a. Nature. 2009 Feb 12;457(7231):854-8. doi: 10.1038/nature07730. Nature. 2009. PMID: 19212405 Free PMC article.
Large-scale discovery of enhancers from human heart tissue.
May D, Blow MJ, Kaplan T, McCulley DJ, Jensen BC, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Wright C, Afzal V, Simpson PC, Rubin EM, Black BL, Bristow J, Pennacchio LA, Visel A. May D, et al. Among authors: holt a. Nat Genet. 2011 Dec 4;44(1):89-93. doi: 10.1038/ng.1006. Nat Genet. 2011. PMID: 22138689 Free PMC article.
ChIP-Seq identification of weakly conserved heart enhancers.
Blow MJ, McCulley DJ, Li Z, Zhang T, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Wright C, Chen F, Afzal V, Bristow J, Ren B, Black BL, Rubin EM, Visel A, Pennacchio LA. Blow MJ, et al. Among authors: holt a. Nat Genet. 2010 Sep;42(9):806-10. doi: 10.1038/ng.650. Epub 2010 Aug 22. Nat Genet. 2010. PMID: 20729851 Free PMC article.
616 results