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Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer.
Topper MJ, Vaz M, Chiappinelli KB, DeStefano Shields CE, Niknafs N, Yen RC, Wenzel A, Hicks J, Ballew M, Stone M, Tran PT, Zahnow CA, Hellmann MD, Anagnostou V, Strissel PL, Strick R, Velculescu VE, Baylin SB. Topper MJ, et al. Among authors: stone m. Cell. 2017 Nov 30;171(6):1284-1300.e21. doi: 10.1016/j.cell.2017.10.022. Cell. 2017. PMID: 29195073 Free PMC article.
Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden.
Stone ML, Chiappinelli KB, Li H, Murphy LM, Travers ME, Topper MJ, Mathios D, Lim M, Shih IM, Wang TL, Hung CF, Bhargava V, Wiehagen KR, Cowley GS, Bachman KE, Strick R, Strissel PL, Baylin SB, Zahnow CA. Stone ML, et al. Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10981-E10990. doi: 10.1073/pnas.1712514114. Epub 2017 Dec 4. Proc Natl Acad Sci U S A. 2017. PMID: 29203668 Free PMC article.
Reply to Haffner et al.: DNA hypomethylation renders tumors more immunogenic.
Stone ML, Chiappinelli KB, Li H, Murphy LM, Travers ME, Topper MJ, Mathios D, Lim M, Shih IM, Wang TL, Hung CF, Bhargava V, Wiehagen KR, Cowley GS, Bachman KE, Strick R, Strissel PL, Baylin SB, Zahnow CA. Stone ML, et al. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8583-E8584. doi: 10.1073/pnas.1811015115. Epub 2018 Sep 4. Proc Natl Acad Sci U S A. 2018. PMID: 30181297 Free PMC article. No abstract available.
Multimodal immune phenotyping reveals microbial-T cell interactions that shape pancreatic cancer.
Li Y, Chang RB, Stone ML, Delman D, Markowitz K, Xue Y, Coho H, Herrera VM, Li JH, Zhang L, Choi-Bose S, Giannone M, Shin SM, Coyne EM, Hernandez A, Gross NE, Charmsaz S, Ho WJ, Lee JW, Beatty GL. Li Y, et al. Among authors: stone ml. Cell Rep Med. 2024 Feb 20;5(2):101397. doi: 10.1016/j.xcrm.2024.101397. Epub 2024 Feb 1. Cell Rep Med. 2024. PMID: 38307029 Free PMC article.
Stromal reprogramming overcomes resistance to RAS-MAPK inhibition to improve pancreas cancer responses to cytotoxic and immune therapy.
Liu X, Baer JM, Stone ML, Knolhoff BL, Hogg GD, Turner MC, Kao YL, Weinstein AG, Ahmad F, Chen J, Schmidt AD, Klomp JA, Coho H, Coho KS, Coma S, Pachter JA, Bryant KL, Kang LI, Lim KH, Beatty GL, DeNardo DG. Liu X, et al. Among authors: stone ml. Sci Transl Med. 2024 Oct 23;16(770):eado2402. doi: 10.1126/scitranslmed.ado2402. Epub 2024 Oct 23. Sci Transl Med. 2024. PMID: 39441902
Hepatocytes coordinate immune evasion in cancer via release of serum amyloid A proteins.
Stone ML, Lee J, Lee JW, Coho H, Tariveranmoshabad M, Wattenberg MM, Choi H, Herrera VM, Xue Y, Choi-Bose S, Zingone SK, Patel D, Markowitz K, Delman D, Balachandran VP, Beatty GL. Stone ML, et al. Nat Immunol. 2024 May;25(5):755-763. doi: 10.1038/s41590-024-01820-1. Epub 2024 Apr 19. Nat Immunol. 2024. PMID: 38641718
3,178 results