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Kinase mutations in cancer: chinks in the enemy's armour?
Di Nicolantonio F, Bardelli A. Di Nicolantonio F, et al. Among authors: bardelli a. Curr Opin Oncol. 2006 Jan;18(1):69-76. doi: 10.1097/01.cco.0000198020.91724.48. Curr Opin Oncol. 2006. PMID: 16357567 Review.
Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses.
Di Nicolantonio F, Arena S, Gallicchio M, Zecchin D, Martini M, Flonta SE, Stella GM, Lamba S, Cancelliere C, Russo M, Geuna M, Appendino G, Fantozzi R, Medico E, Bardelli A. Di Nicolantonio F, et al. Among authors: bardelli a. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20864-9. doi: 10.1073/pnas.0808757105. Epub 2008 Dec 23. Proc Natl Acad Sci U S A. 2008. PMID: 19106301 Free PMC article.
PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies.
Sartore-Bianchi A, Martini M, Molinari F, Veronese S, Nichelatti M, Artale S, Di Nicolantonio F, Saletti P, De Dosso S, Mazzucchelli L, Frattini M, Siena S, Bardelli A. Sartore-Bianchi A, et al. Among authors: bardelli a. Cancer Res. 2009 Mar 1;69(5):1851-7. doi: 10.1158/0008-5472.CAN-08-2466. Epub 2009 Feb 17. Cancer Res. 2009. PMID: 19223544
Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-Ras(G13D).
Palmioli A, Sacco E, Airoldi C, Di Nicolantonio F, D'Urzo A, Shirasawa S, Sasazuki T, Di Domizio A, De Gioia L, Martegani E, Bardelli A, Peri F, Vanoni M. Palmioli A, et al. Among authors: bardelli a. Biochem Biophys Res Commun. 2009 Sep 4;386(4):593-7. doi: 10.1016/j.bbrc.2009.06.069. Epub 2009 Jun 18. Biochem Biophys Res Commun. 2009. PMID: 19540195 Free article.
368 results