Murphy JA - Search Results

1

Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition.

Dalton SE, Dittus L, Thomas DA, Convery MA, Nunes J, Bush JT, Evans JP, Werner T, Bantscheff M, Murphy JA, Campos S. Dalton SE, et al. Among authors: murphy ja. J Am Chem Soc. 2018 Jan 24;140(3):932-939. doi: 10.1021/jacs.7b08979. Epub 2018 Jan 9. J Am Chem Soc. 2018. PMID: 29232121 Free article.

2

One-carbon extrusion from a tetraazafulvalene. Isolation of aldehydes and a study of their origin.

Murphy JA, Schoenebeck F, Findlay NJ, Thomson DW, Zhou SZ, Garnier J. Murphy JA, et al. J Am Chem Soc. 2009 May 13;131(18):6475-9. doi: 10.1021/ja8092746. J Am Chem Soc. 2009. PMID: 19415936 Free PMC article.

3

Amidine dications as superelectrophiles.

Corr MJ, Roydhouse MD, Gibson KF, Zhou SZ, Kennedy AR, Murphy JA. Corr MJ, et al. Among authors: murphy ja. J Am Chem Soc. 2009 Dec 16;131(49):17980-5. doi: 10.1021/ja908191k. J Am Chem Soc. 2009. PMID: 19916499 Free PMC article.

4

Overturning established chemoselectivities: selective reduction of arenes over malonates and cyanoacetates by photoactivated organic electron donors.

Doni E, Mondal B, O'Sullivan S, Tuttle T, Murphy JA. Doni E, et al. Among authors: murphy ja. J Am Chem Soc. 2013 Jul 31;135(30):10934-7. doi: 10.1021/ja4050168. Epub 2013 Jul 19. J Am Chem Soc. 2013. PMID: 23859883 Free PMC article.

5

Identifying the roles of amino acids, alcohols and 1,2-diamines as mediators in coupling of haloarenes to arenes.

Zhou S, Doni E, Anderson GM, Kane RG, MacDougall SW, Ironmonger VM, Tuttle T, Murphy JA. Zhou S, et al. Among authors: murphy ja. J Am Chem Soc. 2014 Dec 24;136(51):17818-26. doi: 10.1021/ja5101036. Epub 2014 Dec 12. J Am Chem Soc. 2014. PMID: 25474411 Free article.

6

KOtBu: A Privileged Reagent for Electron Transfer Reactions?

Barham JP, Coulthard G, Emery KJ, Doni E, Cumine F, Nocera G, John MP, Berlouis LE, McGuire T, Tuttle T, Murphy JA. Barham JP, et al. Among authors: murphy ja. J Am Chem Soc. 2016 Jun 15;138(23):7402-10. doi: 10.1021/jacs.6b03282. Epub 2016 May 26. J Am Chem Soc. 2016. PMID: 27183183 Free article.

7

Contra-thermodynamic Hydrogen Atom Abstraction in the Selective C-H Functionalization of Trialkylamine N-CH₃ Groups.

Barham JP, John MP, Murphy JA. Barham JP, et al. Among authors: murphy ja. J Am Chem Soc. 2016 Nov 30;138(47):15482-15487. doi: 10.1021/jacs.6b09690. Epub 2016 Nov 18. J Am Chem Soc. 2016. PMID: 27809514 Free article.

8

Electron Transfer Reactions: KO tBu (but not NaO tBu) Photoreduces Benzophenone under Activation by Visible Light.

Nocera G, Young A, Palumbo F, Emery KJ, Coulthard G, McGuire T, Tuttle T, Murphy JA. Nocera G, et al. Among authors: murphy ja. J Am Chem Soc. 2018 Aug 1;140(30):9751-9757. doi: 10.1021/jacs.8b06089. Epub 2018 Jul 24. J Am Chem Soc. 2018. PMID: 29996048 Free article.

9

Dual Roles for Potassium Hydride in Haloarene Reduction: CS_NAr and Single Electron Transfer Reduction via Organic Electron Donors Formed in Benzene.

Barham JP, Dalton SE, Allison M, Nocera G, Young A, John MP, McGuire T, Campos S, Tuttle T, Murphy JA. Barham JP, et al. Among authors: murphy ja. J Am Chem Soc. 2018 Sep 12;140(36):11510-11518. doi: 10.1021/jacs.8b07632. Epub 2018 Aug 30. J Am Chem Soc. 2018. PMID: 30119605 Free article.

10

Hi-JAK-ing the ubiquitin system: The design and physicochemical optimisation of JAK PROTACs.

Shah RR, Redmond JM, Mihut A, Menon M, Evans JP, Murphy JA, Bartholomew MA, Coe DM. Shah RR, et al. Among authors: murphy ja. Bioorg Med Chem. 2020 Mar 1;28(5):115326. doi: 10.1016/j.bmc.2020.115326. Epub 2020 Jan 23. Bioorg Med Chem. 2020. PMID: 32001089 Free article.

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