Moreno A - Search Results

1

Monoterpene indole alkaloid azine derivatives as MDR reversal agents.

Paterna A, Khonkarn R, Mulhovo S, Moreno A, Madeira Girio P, Baubichon-Cortay H, Falson P, Ferreira MU. Paterna A, et al. Among authors: moreno a. Bioorg Med Chem. 2018 Jan 15;26(2):421-434. doi: 10.1016/j.bmc.2017.11.052. Epub 2017 Dec 2. Bioorg Med Chem. 2018. PMID: 29233614

2

pHluorin enables insights into the transport mechanism of antiporter Mdr1: R215 is critical for drug/H+ antiport.

Redhu AK, Khandelwal NK, Banerjee A, Moreno A, Falson P, Prasad R. Redhu AK, et al. Among authors: moreno a. Biochem J. 2016 Oct 1;473(19):3127-45. doi: 10.1042/BCJ20160407. Epub 2016 Jul 18. Biochem J. 2016. PMID: 27433020

3

Atomic modelling and systematic mutagenesis identify residues in multiple drug binding sites that are essential for drug resistance in the major Candida transporter Cdr1.

Nim S, Lobato LG, Moreno A, Chaptal V, Rawal MK, Falson P, Prasad R. Nim S, et al. Among authors: moreno a. Biochim Biophys Acta. 2016 Nov;1858(11):2858-2870. doi: 10.1016/j.bbamem.2016.08.011. Epub 2016 Aug 25. Biochim Biophys Acta. 2016. PMID: 27569110 Free article.

4

Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties.

Gilson P, Josa-Prado F, Beauvineau C, Naud-Martin D, Vanwonterghem L, Mahuteau-Betzer F, Moreno A, Falson P, Lafanechère L, Frachet V, Coll JL, Fernando Díaz J, Hurbin A, Busser B. Gilson P, et al. Among authors: moreno a. Sci Rep. 2017 Aug 31;7(1):10209. doi: 10.1038/s41598-017-09491-9. Sci Rep. 2017. PMID: 28860487 Free PMC article.

5

Molecular Basis of Substrate Polyspecificity of the Candida albicans Mdr1p Multidrug/H⁺ Antiporter.

Redhu AK, Banerjee A, Shah AH, Moreno A, Rawal MK, Nair R, Falson P, Prasad R. Redhu AK, et al. Among authors: moreno a. J Mol Biol. 2018 Mar 2;430(5):682-694. doi: 10.1016/j.jmb.2018.01.005. Epub 2018 Jan 16. J Mol Biol. 2018. PMID: 29341887

6

W1038 near D-loop of NBD2 is a focal point for inter-domain communication in multidrug transporter Cdr1 of Candida albicans.

Banerjee A, Shah AH, Redhu AK, Moreno A, Falson P, Prasad R. Banerjee A, et al. Among authors: moreno a. Biochim Biophys Acta Biomembr. 2018 May;1860(5):965-972. doi: 10.1016/j.bbamem.2018.01.022. Epub 2018 Feb 1. Biochim Biophys Acta Biomembr. 2018. PMID: 29410026 Free article.

7

Optimizing the flavanone core toward new selective nitrogen-containing modulators of ABC transporters.

Ferreira RJ, Baptista R, Moreno A, Madeira PG, Khonkarn R, Baubichon-Cortay H, Dos Santos DJ, Falson P, Ferreira MU. Ferreira RJ, et al. Among authors: moreno a. Future Med Chem. 2018 Apr 1;10(7):725-741. doi: 10.4155/fmc-2017-0228. Epub 2018 Mar 23. Future Med Chem. 2018. PMID: 29570361

8

Methyl-cyclopentadienyl Ruthenium Compounds with 2,2'-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential.

Côrte-Real L, Teixeira RG, Gírio P, Comsa E, Moreno A, Nasr R, Baubichon-Cortay H, Avecilla F, Marques F, Robalo MP, Mendes P, Ramalho JPP, Garcia MH, Falson P, Valente A. Côrte-Real L, et al. Among authors: moreno a. Inorg Chem. 2018 Apr 16;57(8):4629-4639. doi: 10.1021/acs.inorgchem.8b00358. Epub 2018 Apr 3. Inorg Chem. 2018. PMID: 29611696

9

5-Oxo-hexahydroquinoline derivatives as modulators of P-gp, MRP1 and BCRP transporters to overcome multidrug resistance in cancer cells.

Ranjbar S, Khonkarn R, Moreno A, Baubichon-Cortay H, Miri R, Khoshneviszadeh M, Saso L, Edraki N, Falson P, Firuzi O. Ranjbar S, et al. Among authors: moreno a. Toxicol Appl Pharmacol. 2019 Jan 1;362:136-149. doi: 10.1016/j.taap.2018.10.025. Epub 2018 Nov 2. Toxicol Appl Pharmacol. 2019. PMID: 30391378

10

Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand.

Côrte-Real L, Karas B, Gírio P, Moreno A, Avecilla F, Marques F, Buckley BT, Cooper KR, Doherty C, Falson P, Garcia MH, Valente A. Côrte-Real L, et al. Among authors: moreno a. Eur J Med Chem. 2019 Feb 1;163:853-863. doi: 10.1016/j.ejmech.2018.12.022. Epub 2018 Dec 12. Eur J Med Chem. 2019. PMID: 30579125 Free PMC article.

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