Rubinsztein DC - Search Results

1

Autophagy impairment in Parkinson's disease.

Karabiyik C, Lee MJ, Rubinsztein DC. Karabiyik C, et al. Among authors: rubinsztein dc. Essays Biochem. 2017 Dec 12;61(6):711-720. doi: 10.1042/EBC20170023. Print 2017 Dec 12. Essays Biochem. 2017. PMID: 29233880 Review.

2

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy.

Ravikumar B, Duden R, Rubinsztein DC. Ravikumar B, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2002 May 1;11(9):1107-17. doi: 10.1093/hmg/11.9.1107. Hum Mol Genet. 2002. PMID: 11978769

3

Raised intracellular glucose concentrations reduce aggregation and cell death caused by mutant huntingtin exon 1 by decreasing mTOR phosphorylation and inducing autophagy.

Ravikumar B, Stewart A, Kita H, Kato K, Duden R, Rubinsztein DC. Ravikumar B, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2003 May 1;12(9):985-94. doi: 10.1093/hmg/ddg109. Hum Mol Genet. 2003. PMID: 12700167

4

Alpha-Synuclein is degraded by both autophagy and the proteasome.

Webb JL, Ravikumar B, Atkins J, Skepper JN, Rubinsztein DC. Webb JL, et al. Among authors: rubinsztein dc. J Biol Chem. 2003 Jul 4;278(27):25009-13. doi: 10.1074/jbc.M300227200. Epub 2003 Apr 28. J Biol Chem. 2003. PMID: 12719433 Free article.

5

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.

Ravikumar B, Vacher C, Berger Z, Davies JE, Luo S, Oroz LG, Scaravilli F, Easton DF, Duden R, O'Kane CJ, Rubinsztein DC. Ravikumar B, et al. Among authors: rubinsztein dc. Nat Genet. 2004 Jun;36(6):585-95. doi: 10.1038/ng1362. Epub 2004 May 16. Nat Genet. 2004. PMID: 15146184

6

Microtubule disruption inhibits autophagosome-lysosome fusion: implications for studying the roles of aggresomes in polyglutamine diseases.

Webb JL, Ravikumar B, Rubinsztein DC. Webb JL, et al. Among authors: rubinsztein dc. Int J Biochem Cell Biol. 2004 Dec;36(12):2541-50. doi: 10.1016/j.biocel.2004.02.003. Int J Biochem Cell Biol. 2004. PMID: 15325591

7

Can autophagy protect against neurodegeneration caused by aggregate-prone proteins?

Ravikumar B, Rubinsztein DC. Ravikumar B, et al. Among authors: rubinsztein dc. Neuroreport. 2004 Nov 15;15(16):2443-5. doi: 10.1097/00001756-200411150-00001. Neuroreport. 2004. PMID: 15538170 Review.

8

Autophagy and its possible roles in nervous system diseases, damage and repair.

Rubinsztein DC, DiFiglia M, Heintz N, Nixon RA, Qin ZH, Ravikumar B, Stefanis L, Tolkovsky A. Rubinsztein DC, et al. Autophagy. 2005 Apr;1(1):11-22. doi: 10.4161/auto.1.1.1513. Epub 2005 Apr 30. Autophagy. 2005. PMID: 16874045 Review.

9

Dyneins, autophagy, aggregation and neurodegeneration.

Rubinsztein DC, Ravikumar B, Acevedo-Arozena A, Imarisio S, O'Kane CJ, Brown SD. Rubinsztein DC, et al. Autophagy. 2005 Oct-Dec;1(3):177-8. doi: 10.4161/auto.1.3.2050. Epub 2005 Oct 21. Autophagy. 2005. PMID: 16874055 Review.

10

Protective roles for induction of autophagy in multiple proteinopathies.

Menzies FM, Ravikumar B, Rubinsztein DC. Menzies FM, et al. Among authors: rubinsztein dc. Autophagy. 2006 Jul-Sep;2(3):224-5. doi: 10.4161/auto.2696. Epub 2006 Jul 10. Autophagy. 2006. PMID: 16874096 Review.

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