Swan MK - Search Results

1

New 4-Amino-1,2,3-Triazole Inhibitors of Indoleamine 2,3-Dioxygenase Form a Long-Lived Complex with the Enzyme and Display Exquisite Cellular Potency.

Alexandre JAC, Swan MK, Latchem MJ, Boyall D, Pollard JR, Hughes SW, Westcott J. Alexandre JAC, et al. Among authors: swan mk. Chembiochem. 2018 Mar 16;19(6):552-561. doi: 10.1002/cbic.201700560. Epub 2018 Jan 31. Chembiochem. 2018. PMID: 29240291

2

Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA.

Swan MK, Legris V, Tanner A, Reaper PM, Vial S, Bordas R, Pollard JR, Charlton PA, Golec JM, Bertrand JA. Swan MK, et al. Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1465-75. doi: 10.1107/S139900471400501X. Epub 2014 Apr 30. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24816114

3

Targeting the PPM1D phenotype; 2,4-bisarylthiazoles cause highly selective apoptosis in PPM1D amplified cell-lines.

Cheeseman MD, Faisal A, Rayter S, Barbeau OR, Kalusa A, Westlake M, Burke R, Swan M, van Montfort R, Linardopoulos S, Jones K. Cheeseman MD, et al. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3469-74. doi: 10.1016/j.bmcl.2014.05.067. Epub 2014 May 29. Bioorg Med Chem Lett. 2014. PMID: 24953599

4

Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta.

Swan MK, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Swan MK, et al. Nat Struct Mol Biol. 2009 Sep;16(9):979-86. doi: 10.1038/nsmb.1663. Epub 2009 Aug 30. Nat Struct Mol Biol. 2009. PMID: 19718023 Free PMC article.

5

Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion.

Vasquez-Del Carpio R, Silverstein TD, Lone S, Swan MK, Choudhury JR, Johnson RE, Prakash S, Prakash L, Aggarwal AK. Vasquez-Del Carpio R, et al. Among authors: swan mk. PLoS One. 2009 Jun 2;4(6):e5766. doi: 10.1371/journal.pone.0005766. PLoS One. 2009. PMID: 19492058 Free PMC article.

6

Structure of the human Rev1-DNA-dNTP ternary complex.

Swan MK, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Swan MK, et al. J Mol Biol. 2009 Jul 24;390(4):699-709. doi: 10.1016/j.jmb.2009.05.026. Epub 2009 May 21. J Mol Biol. 2009. PMID: 19464298 Free PMC article.

7

Crystal structure of pi initiator protein-iteron complex of plasmid R6K: implications for initiation of plasmid DNA replication.

Swan MK, Bastia D, Davies C. Swan MK, et al. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18481-6. doi: 10.1073/pnas.0609046103. Epub 2006 Nov 21. Proc Natl Acad Sci U S A. 2006. PMID: 17124167 Free PMC article.

8

Mutagenesis of catalytically important residues of cupin type phosphoglucose isomerase from Archaeoglobus fulgidus.

Hansen T, Schlichting B, Grötzinger J, Swan MK, Davies C, Schönheit P. Hansen T, et al. Among authors: swan mk. FEBS J. 2005 Dec;272(24):6266-75. doi: 10.1111/j.1742-4658.2005.05007.x. FEBS J. 2005. PMID: 16336264 Free article.

9

Structural basis for phosphomannose isomerase activity in phosphoglucose isomerase from Pyrobaculum aerophilum: a subtle difference between distantly related enzymes.

Swan MK, Hansen T, Schönheit P, Davies C. Swan MK, et al. Biochemistry. 2004 Nov 9;43(44):14088-95. doi: 10.1021/bi048608y. Biochemistry. 2004. PMID: 15518558

10

The crystal structure of mouse phosphoglucose isomerase at 1.6A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening.

Solomons JT, Zimmerly EM, Burns S, Krishnamurthy N, Swan MK, Krings S, Muirhead H, Chirgwin J, Davies C. Solomons JT, et al. Among authors: swan mk. J Mol Biol. 2004 Sep 17;342(3):847-60. doi: 10.1016/j.jmb.2004.07.085. J Mol Biol. 2004. PMID: 15342241

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