Downward J - Search Results

1

Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA.

Coelho MA, de Carné Trécesson S, Rana S, Zecchin D, Moore C, Molina-Arcas M, East P, Spencer-Dene B, Nye E, Barnouin K, Snijders AP, Lai WS, Blackshear PJ, Downward J. Coelho MA, et al. Among authors: downward j. Immunity. 2017 Dec 19;47(6):1083-1099.e6. doi: 10.1016/j.immuni.2017.11.016. Epub 2017 Dec 12. Immunity. 2017. PMID: 29246442 Free PMC article.

2

Ras signalling and apoptosis.

Downward J. Downward J. Curr Opin Genet Dev. 1998 Feb;8(1):49-54. doi: 10.1016/s0959-437x(98)80061-0. Curr Opin Genet Dev. 1998. PMID: 9529605 Review.

3

Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression.

Delpuech O, Griffiths B, East P, Essafi A, Lam EW, Burgering B, Downward J, Schulze A. Delpuech O, et al. Among authors: downward j. Mol Cell Biol. 2007 Jul;27(13):4917-30. doi: 10.1128/MCB.01789-06. Epub 2007 Apr 23. Mol Cell Biol. 2007. PMID: 17452451 Free PMC article.

4

Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice.

Gupta S, Ramjaun AR, Haiko P, Wang Y, Warne PH, Nicke B, Nye E, Stamp G, Alitalo K, Downward J. Gupta S, et al. Among authors: downward j. Cell. 2007 Jun 1;129(5):957-68. doi: 10.1016/j.cell.2007.03.051. Cell. 2007. PMID: 17540175 Free article.

5

Ras and phosphoinositide 3-kinase: partners in development and tumorigenesis.

Ramjaun AR, Downward J. Ramjaun AR, et al. Among authors: downward j. Cell Cycle. 2007 Dec 1;6(23):2902-5. doi: 10.4161/cc.6.23.4996. Epub 2007 Aug 31. Cell Cycle. 2007. PMID: 17993782 Review.

6

SnapShot: Ras Signaling.

Cully M, Downward J. Cully M, et al. Among authors: downward j. Cell. 2008 Jun 27;133(7):1292-1292.e1. doi: 10.1016/j.cell.2008.06.020. Cell. 2008. PMID: 18585361 Free article. No abstract available.

7

Critical role for transcriptional repressor Snail2 in transformation by oncogenic RAS in colorectal carcinoma cells.

Wang Y, Ngo VN, Marani M, Yang Y, Wright G, Staudt LM, Downward J. Wang Y, et al. Among authors: downward j. Oncogene. 2010 Aug 19;29(33):4658-70. doi: 10.1038/onc.2010.218. Epub 2010 Jun 21. Oncogene. 2010. PMID: 20562906 Free PMC article.

8

How to fool a wonder drug: truncate and dimerize.

Molina-Arcas M, Downward J. Molina-Arcas M, et al. Among authors: downward j. Cancer Cell. 2012 Jan 17;21(1):7-9. doi: 10.1016/j.ccr.2011.12.017. Cancer Cell. 2012. PMID: 22264784 Free article.

9

The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer.

Kumar MS, Hancock DC, Molina-Arcas M, Steckel M, East P, Diefenbacher M, Armenteros-Monterroso E, Lassailly F, Matthews N, Nye E, Stamp G, Behrens A, Downward J. Kumar MS, et al. Among authors: downward j. Cell. 2012 Apr 27;149(3):642-55. doi: 10.1016/j.cell.2012.02.059. Cell. 2012. PMID: 22541434 Free article.

10

Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies.

Steckel M, Molina-Arcas M, Weigelt B, Marani M, Warne PH, Kuznetsov H, Kelly G, Saunders B, Howell M, Downward J, Hancock DC. Steckel M, et al. Among authors: downward j. Cell Res. 2012 Aug;22(8):1227-45. doi: 10.1038/cr.2012.82. Epub 2012 May 22. Cell Res. 2012. PMID: 22613949 Free PMC article.

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