Zhang R - Search Results

1

BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian Cancer.

Karakashev S, Zhu H, Yokoyama Y, Zhao B, Fatkhutdinov N, Kossenkov AV, Wilson AJ, Simpkins F, Speicher D, Khabele D, Bitler BG, Zhang R. Karakashev S, et al. Among authors: zhang r. Cell Rep. 2017 Dec 19;21(12):3398-3405. doi: 10.1016/j.celrep.2017.11.095. Cell Rep. 2017. PMID: 29262321 Free PMC article.

2

Wnt5a suppresses epithelial ovarian cancer by promoting cellular senescence.

Bitler BG, Nicodemus JP, Li H, Cai Q, Wu H, Hua X, Li T, Birrer MJ, Godwin AK, Cairns P, Zhang R. Bitler BG, et al. Among authors: zhang r. Cancer Res. 2011 Oct 1;71(19):6184-94. doi: 10.1158/0008-5472.CAN-11-1341. Epub 2011 Aug 4. Cancer Res. 2011. PMID: 21816908 Free PMC article.

3

Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence.

Tu Z, Aird KM, Bitler BG, Nicodemus JP, Beeharry N, Xia B, Yen TJ, Zhang R. Tu Z, et al. Among authors: zhang r. Dev Cell. 2011 Dec 13;21(6):1077-91. doi: 10.1016/j.devcel.2011.10.010. Epub 2011 Dec 1. Dev Cell. 2011. PMID: 22137763 Free PMC article.

4

ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches.

Li H, Bitler BG, Vathipadiekal V, Maradeo ME, Slifker M, Creasy CL, Tummino PJ, Cairns P, Birrer MJ, Zhang R. Li H, et al. Among authors: zhang r. Cancer Prev Res (Phila). 2012 Mar;5(3):484-91. doi: 10.1158/1940-6207.CAPR-11-0414. Epub 2011 Dec 5. Cancer Prev Res (Phila). 2012. PMID: 22144423 Free PMC article.

5

NF-YA underlies EZH2 upregulation and is essential for proliferation of human epithelial ovarian cancer cells.

Garipov A, Li H, Bitler BG, Thapa RJ, Balachandran S, Zhang R. Garipov A, et al. Among authors: zhang r. Mol Cancer Res. 2013 Apr;11(4):360-9. doi: 10.1158/1541-7786.MCR-12-0661. Epub 2013 Jan 29. Mol Cancer Res. 2013. PMID: 23360797 Free PMC article.

6

Identification of multiple novel protein biomarkers shed by human serous ovarian tumors into the blood of immunocompromised mice and verified in patient sera.

Beer LA, Wang H, Tang HY, Cao Z, Chang-Wong T, Tanyi JL, Zhang R, Liu Q, Speicher DW. Beer LA, et al. Among authors: zhang r. PLoS One. 2013;8(3):e60129. doi: 10.1371/journal.pone.0060129. Epub 2013 Mar 27. PLoS One. 2013. PMID: 23544127 Free PMC article.

7

Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence.

Aird KM, Zhang G, Li H, Tu Z, Bitler BG, Garipov A, Wu H, Wei Z, Wagner SN, Herlyn M, Zhang R. Aird KM, et al. Among authors: zhang r, zhang g. Cell Rep. 2013 Apr 25;3(4):1252-65. doi: 10.1016/j.celrep.2013.03.004. Epub 2013 Apr 4. Cell Rep. 2013. PMID: 23562156 Free PMC article.

8

A high-content screening assay for small-molecule modulators of oncogene-induced senescence.

Bitler BG, Fink LS, Wei Z, Peterson JR, Zhang R. Bitler BG, et al. Among authors: zhang r. J Biomol Screen. 2013 Oct;18(9):1054-61. doi: 10.1177/1087057113491827. Epub 2013 Jun 3. J Biomol Screen. 2013. PMID: 23733845 Free PMC article.

9

Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition.

Amatangelo MD, Garipov A, Li H, Conejo-Garcia JR, Speicher DW, Zhang R. Amatangelo MD, et al. Among authors: zhang r. Cell Cycle. 2013 Jul 1;12(13):2113-9. doi: 10.4161/cc.25163. Epub 2013 Jun 10. Cell Cycle. 2013. PMID: 23759589 Free PMC article.

10

Protein isoform-specific validation defines multiple chloride intracellular channel and tropomyosin isoforms as serological biomarkers of ovarian cancer.

Tang HY, Beer LA, Tanyi JL, Zhang R, Liu Q, Speicher DW. Tang HY, et al. Among authors: zhang r. J Proteomics. 2013 Aug 26;89:165-78. doi: 10.1016/j.jprot.2013.06.016. Epub 2013 Jun 21. J Proteomics. 2013. PMID: 23792823 Free PMC article. Clinical Trial.

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